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- 详细信息
- 技术资料
- 免疫原:
CD44
- 亚型:
rat IgG2bκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
IM7.8.1
- 标记物:
Biotin
- 适应物种:
mouse, non-human primate, other
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度:
1:10
- 靶点:
CD44
- 抗体英文名:
CD44 Antibody, anti-mouse
- 抗体名:
CD44 Antibody, anti-mouse
- 规格:
30 µg in 1 mL
Discrimination of mouse antigen-experienced T cells (CD44high) from naive T cells (CD44low)Mouse CD44 is also known as Pgp-1, HCELL, HUTCH-I, HCAM, HERMES, and Ly-24. Clone IM7 reacts with murine CD44, an 80–95 kDa membrane glycoprotein. It is expressed by a variety of hematopoetic and non-hematopoetic cells. Different isoforms are generated by alternative splicing. Clone IM7 reacts with all isoforms and both allelic forms of CD44. CD44 functions as a receptor for hyaluronic acid (HA) and mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). CD44 expression is upregulated on naive T cells upon activation and high CD44 expression is maintained on memory T cells. Therefore, CD44 is often used to discriminate CD44highantigen-experienced T cells from CD44low (CD62L+) naive T cells.
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CD44 Antibody, anti-mouse, Biotin, 30 µg in 1 mL
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