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- 详细信息
- 技术资料
- 免疫原:
CX3CR1
- 亚型:
rat IgG2bκ
- 形态:
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件:
避光,2-8℃
- 克隆性:
2A9-1
- 标记物:
Biotin
- 适应物种:
human
- 保质期:
24个月
- 供应商:
Miltenyi Biotec
- 宿主:
rat
- 应用范围:
Flow cytometry
- 浓度:
1:50
- 靶点:
CX3CR1
- 抗体英文名:
CX3CR1 Antibody, anti-human
- 抗体名:
CX3CR1 Antibody, anti-human
- 规格:
100 tests in 200 µL
Detection of human CX3CR1+ cellsCX3CR1 is a transmembrane chemokine receptor with a molecular mass of 40 kDa. It binds the chemokine CX3CL1, also known as fractalkine or neurotactin. Binding of CX3CR1 to the membrane‑bound form of fractalkine promotes cell-cell adhesion, wheras the soluble form induces cell migration of CX3CR1-bearing cells such as monocytes, NK cells, T cells, dendritic cells (DCs), and macrophages including microglia.¹ CX3CR1 plays also an important role in the formation of transepithelial dendrites by intestinal DCs.² Failure in the fractalkine/CX3CR1 interaction may contribute to the development of several inflammatory diseases including atherosclerosis, psoriasis, rheumatoid arthritis, and experimental autoimmune myositis.
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CX3CR1 Antibody, anti-human, Biotin, 100 tests in 200 µL
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