- 询价
- Miltenyi Biotec
- 德国
- 130-128-284
- 2025年12月09日
- Flow cytometry, Mass cytometry
- human cell line
- human
企业认证
相关产品推荐更多 >
Plexin-B1 Antibody, anti-human, PE, REAfinity™, 30 tests in 60 µL
询价
Cytokeratin 10 Antibody, anti-human, PE, REAfinity™, 200 µL
询价
CD4 (Domain 1) Antibody, anti-rat, PE, REAfinity™, 9 µg in 300 µL
询价PSMA Antibody, anti-human, Vio® Bright B515, REAfinity™, 100 tests in 200 µL
询价CD3 Antibody, anti-non-human primate, PE-Vio® 770, 30 tests in 60 µL
询价
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
TIGIT
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA1004
- 标记物：
Vio Bright V423
- 适应物种：
human
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, Mass cytometry
- 浓度：
1:50
- 抗体英文名：
TIGIT Antibody, anti-human, REAfinity™
- 抗体名：
TIGIT Antibody, anti-human, REAfinity™
- 规格：
30 tests in 60 µL
Identification and enumeration of TIGIT+ cells by flow cytometryClone REA1004 recognizes the human T cell immunoglobulin and ITIM domain (TIGIT) antigen, a protein containing an immunoglobulin variable (IgV) domain, a transmembrane domain, and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on T cells, including Treg cells and memory subsets, as well as on natural killer (NK) cells. The poliovirus receptor (PVR; also called NECL5 or CD155) is a high-affinity coreceptor for TIGIT that is highly expressed on dendritic cells (DCs), fibroblasts, endothelial cells, and some tumor cells. The interaction of TIGIT with PVR on DCs leads to the down-regulation of pro-inflammatory cytokine secretion and the induction of interleukin 10 (IL-10) production in DCs, exerting an inhibitory effect on T cell activation. | Additional information: Clone REA1004 displays negligible binding to Fc receptors.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验该产品被引用文献
Yu, X. et al. (2009) The surface protein TIGIT suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells. Nat Immunol 10 (1): 48–57. | Levin, S. D. et al. (2011) Vstm3 is a member of the CD28 family and an important modulator of T-cell function. Eur. J. Immunol. 41 (4): 902–915.
技术资料暂无技术资料 索取技术资料
文献支持
TIGIT Antibody, anti-human, Vio® Bright V423, REAfinity™, 30 tests in 60 µL
询价
