- 询价
- Miltenyi Biotec
- 德国
- 130-116-376
- 2025年12月09日
- Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- human cell line
- human, mouse
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- 详细信息
- 技术资料
- 免疫原：
AN2
- 亚型：
recombinant human IgG1
- 形态：
Reagents are supplied in buffer containing stabilizer and 0.05% sodium azide.
- 保存条件：
避光，2-8℃
- 克隆性：
REA989
- 标记物：
PE
- 适应物种：
human, mouse
- 保质期：
24个月
- 供应商：
Miltenyi Biotec
- 宿主：
human cell line
- 应用范围：
Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry
- 浓度：
1:50
- 靶点：
AN2
- 抗体英文名：
AN2 Antibody, anti-human/mouse, REAfinity™
- 抗体名：
AN2 Antibody, anti-human/mouse, REAfinity™
- 规格：
100 tests in 200 µL
Identification and enumeration of AN2+ cells by flow cytometryClone REA989 recognizes the human and mouse AN2 antigen. AN2 is the mouse homolog of the rat NG2 and human Melanoma (MCSP) proteins. NG2 is a chondroitin sulfate glycoprotein that is expressed by glial progenitor cells in the developing and adult central nervous system (CNS) and by immature Schwann cells. NG2/AN2+ glia has been identified as a fourth major glial cell type in the mammalian CNS that is distinct from other cell types. NG2/AN2+ cells are precursors of oligodendrocytes and some protoplasmic astrocytes in the gray matter. NG2/AN2 expression is down-regulated before the cells undergo terminal differentiation. However, a population of NG2/AN2+ cells remains in the white and gray matter after oligodendrocytes are generated. NG2/AN2+ glial cells participate in neuron-glial circuits by receiving presynaptic input from neurons and responding to neurotransmitters released by synapses. Many highly migratory neural tumors including melanomas express NG2/AN2. | Additional information: Clone REA989 displays negligible binding to Fc receptors.
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AN2 Antibody, anti-human/mouse, PE, REAfinity™, 100 tests in 200 µL
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