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- 文献和实验
- 技术资料
- 抗体名:
Stargazin Antibody (APC) 抗体
- 抗体英文名:
Stargazin Antibody (APC)
- 靶点:
Stargazin
- 浓度:
1 mg/ml
- 应用范围:
ICC, IF, WB
- 宿主:
Mouse
- 适应物种:
Human, Mouse, Rat
- 保质期:
12 months from date of receipt.
- 抗原来源:
详询
- 目录编号:
orb150200
- 级别:
科研
- 库存:
99
- 供应商:
Biorbyt
- 标记物:
APC
- 克隆性:
Monoclonal
- 保存条件:
详询
- 亚型:
IgG2A
- 免疫原:
详询
- 规格:
100 ug
描述: Mouse monoclonal to TARP Gamma2 (APC). Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state. There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival..
克隆号: N245/36 (Formerly sold as S245-36)
别名: CACNG2, Calcium channel voltage dependent gamma subunit 2, CaV gamma 2, Ipr328, MGC123981, MGC138502, MGC138504, Voltage-dependent calcium channel gamma-2 subunit, Neuronal voltage-gated calcium channel gamma-2 subunit, Stargazin, Stg, Stargazer, TARP, TARP gamma-2, Transmembrane AMPAR regulatory protein gamma-2, AW060990, B230105C07Rik, B930041E13Rik, Wag, Waggler
应用稀释比例: WB (1:1000), ICC/IF (1:100)
应用说明: 1 µg/ml was sufficient for detection of TARP Gamma2/4/8 in 20 µg of rat brain lysate by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
免疫原: Fusion protein amino acids 203-323 (Cytoplasmic C-terminus) of rat TARPGamma2
分子量: 35-55kDa
防腐剂: 95.46mM Phosphate, 2.48mM MES and 2mM EDTA
纯化方法: Protein G Purified
特异性: Detects ~35-55kDa. Does not cross-react with TARPGamma3.
研究领域: Neuroscience
UniProt ID: Q71RJ2
NCBI 参考序列: NP_445803.1
Entrez 基因 ID: 84347
保存条件: Conjugated antibodies should be stored according to the product label
备注: For research use only.


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文献和实验抗体的概念 抗体(antibody, Ab),也叫免疫球蛋白(immunoglobulin, Ig),是血液和组织液中的一类糖蛋白,由B细胞接受抗原刺激后增殖分化成的浆细胞产生,能与相应抗原特异性地结合,是介导体液免疫的重要效应分子。1968年和1972年世界卫生组织和国际免疫学联合会的专门委员会先后决定,将具有抗体活性或化学结构与抗体相似的球蛋白统称为免疫球蛋白。后来研究证实,Ig和Ab在结构及功能上完全一致,因此可认为二者的概念等同。Ig可分为分泌型和跨模型,前者主要存在于血液和组织液中
v468 Chapter 6 细胞内结肠腺瘤样息肉蛋白核定位以及细胞质检测
, and has characterized pathways for the trafficking of APC both into and out of the nucleus.Antibody specificity is an important factor in the determination of APC localization, and in this chapterwe outline a strategy for the unambiguous detection of APC using
Biosynthetic labeling (Sefton Lab) Biotinylation of Antibody (Contributed by Nanci Donacki) 125 I Labeling of Protein using ICl (ScienceXchange) Protein (Antibody) Fluorescent Labeling (Mario Roederer) Gives detailed
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