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- bsm-43703M-Cy3
- 2026年10月17日
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| 产品编号 | bsm-43703M-Cy3 |
| 英文名称 | CD38 Mouse mAb, Cy3 conjugated |
| 中文名称 | Cy3标记的CD38单克隆抗体 |
| 英文别名 | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1; 2'-phospho-ADP-ribosyl cyclase; 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase; 2'-phospho-cyclic-ADP-ribose transferase; ADP-ribosyl cyclase 1; ADPRC 1; Cyclic ADP-ribose hydrolase 1; cADPr hydrolase 1; T10; CD38_HUMAN; CD38_MOUSE; I-19; NIM-R5 antigen. |
| 产品应用 | IF=1:100-500, Flow-Cyt=1ug/Test, ICC/IF=1:50-200 Not yet tested in other applications. |
| 抗体来源 | Mouse |
| 免疫原 | Recombinant human CD38 protein |
| 亚型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Monoclonal |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Cancer > Cancer Metabolism > Response to hypoxia Immunology > Adaptive Immunity > B Cells > CD Immunology > Adaptive Immunity > Regulatory T Cells Metabolism > Pathways and Processes > Metabolism processes > Hypoxia Metabolism > Types of disease > Cancer Microbiology > Organism > Virus > RNA Virus > ssRNA positive strand virus > SARS Coronavirus Stem Cells > Hematopoietic Progenitors > Hematopoietic Stem Cells > Human Lineage Negative Stem Cells > Hematopoietic Progenitors > Lymphoid > B Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Lymphoid > NK Cell Lineage Stem Cells > Hematopoietic Progenitors > Lymphoid > T Lymphocytic Lineage Stem Cells > Hematopoietic Progenitors > Myeloid > Monocytic Lineage Stem Cells > Hematopoietic Progenitors > Surface Molecules |
| 亚细胞定位 | Membrane; Single-pass type II membrane protein. |
| 组织特异性 | Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma. |
| 相似性 | Belongs to the ADP-ribosyl cyclase family. |
| 功能 | Synthesizes cyclic ADP-ribose, a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
| 应用 | 推荐稀释比例 |
| {IF} | {1:100-500} |
| {Flow-Cyt} | {1ug/Test} |
| {ICC/IF} | {1:50-200} |
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RX/RX m，实现自动原位可视化 PD1/PD-L1 的相互作用。使用Red/Atto647N 荧光基团进行检测。 60012 Naveni PD1/PDL1 BOND RX Atto647N 60000 NaveniPlex 可同时检测 PD-1/PD-L1、CD8/MCH1的互作以及CD3。适用于FFPE组织样本。 S0B2187 S-RMab® PD-1 Recombinant Mouse mAb (SDT-R143) PD-1重组鼠抗，应用IHC-P,ICFCM,ICC,WB
) were in contact with the sections for 90 min at room temperature. This was followed by three washes with PBS and the application of the secondary antibodies (antirabbit IgG-Cy3 or anti-mouse IgM-Cy5) for 45 min at room temperature. After being washed
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