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- 详细信息
- 文献和实验
- 技术资料
- 供应商:
上海再康生物科技有限公司
- 库存:
大量
- 靶点:
见官方网站
- 级别:
高
- 目录编号:
AK-221
- 克隆性:
多克隆
- 抗原来源:
见 说 明 书
- 保质期:
6个月
- 抗体英文名:
KCNQ Channel Antibody Explorer Kit
- 抗体名:
KCNQ Channel Antibody Explorer Kit
- 标记物:
见官方网站
- 宿主:
见 说 明 书
- 适应物种:
见官方网站
- 免疫原:
见官方网站
- 亚型:
见官方网站
- 形态:
液体或冻干粉
- 应用范围:
见官方网站
- 浓度:
见官方网站
- 保存条件:
-20°C
- 规格:
14 Vials
KCNQ Channel Antibody Explorer Kit
A Screening Package of KCNQ Channel Antibodies Economically PricedCat #: AK-221
14 Vials
Alomone Labs is pleased to offer the KCNQ Channel Antibody Explorer Kit (#AK-221). This Explorer Kit includes antibodies targeted against KV7 channels and subunits along with their respective peptide control antigen. An ideal tool for screening purposes.
- Compounds
- Scientific Background
- Related Products
| Product Name | Cat # | Size |
|---|---|---|
Anti-KV7.1 (KCNQ1) |
APC-022 | 1 x 50 µl |
Anti-KV7.1 (KCNQ1) (extracellular) |
APC-168 | 1 x 50 µl |
Anti-KV7.3 (KCNQ3) |
APC-051 | 1 x 50 µl |
Anti-KV7.4 |
APC-164 | 1 x 50 µl |
Anti-KV7.5 |
APC-155 | 1 x 50 µl |
Anti-KCNE3 (MiRP2) |
APC-118 | 1 x 50 µl |
Anti-KCNE4 (MiRP3) |
APC-129 | 1 x 50 µl |
KCNQ Channel Antibody Explorer KitScientific Background
The KCNQ family of voltage-gated K+ channels includes 5 known members: KCNQ1 to KCNQ5. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. KCNQ family members can form either homomultimeric or heteromultimeric channels with different functional consequences. For example KCNQ2 and KCNQ3 heteromultimers give rise to a much larger channel current than when either protein is expressed alone, probably due to enhanced plasma membrane expression of the combined channel. Indeed, KCNQ2/KCNQ3 heteromultimers are believed to be the molecular correlates of the so-called M current. This current is a K+ neuronal current that is strongly inhibited by the activation of the M1 subtype of the muscarinic acetylcholine receptor.
KV7.5 is also expressed in visceral smooth muscle4 and skeletal muscle.
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文献和实验RAT/MOUSE GROWTH HORMONE ELISA KIT
polyclonal antibodies, 2) wash away of unbound materials from samples, 3) binding of a second biotinylated anti-Growth Hormone polyclonal antibody to the captured molecules, 4) wash away of unbound materials from samples, 5) conjugation of horseradish
overnight. Next, slides were rinsed with water and covered with blocking solution for 2 h at room temperature. Then, after rinsing with water, AlexaFluor-488 labeled anti-mouse antibody conjugate (33 nM in blocking solution) was added to the sample slides
System (biotinylated probe): DNA - 1µg dNTPs 10X Mix - 5µl Enzyme 10X Mix - 5µl ddH2 O (from the kit) - to 50µl final Mix well and centrifuge briefly; Incubate 1-2 hours at 16°C. Before stopping the reaction, load 1/10 (5µ
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