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- 详细信息
- 技术资料
- 供应商:
上海再康生物科技有限公司
- 库存:
大量
- 靶点:
见官方网站
- 级别:
高
- 目录编号:
AK-221
- 克隆性:
多克隆
- 抗原来源:
见 说 明 书
- 保质期:
6个月
- 抗体英文名:
KCNQ Channel Antibody Explorer Kit
- 抗体名:
KCNQ Channel Antibody Explorer Kit
- 标记物:
见官方网站
- 宿主:
见 说 明 书
- 适应物种:
见官方网站
- 免疫原:
见官方网站
- 亚型:
见官方网站
- 形态:
液体或冻干粉
- 应用范围:
见官方网站
- 浓度:
见官方网站
- 保存条件:
-20°C
- 规格:
14 Vials
KCNQ Channel Antibody Explorer Kit
A Screening Package of KCNQ Channel Antibodies Economically PricedCat #: AK-221
14 Vials
Alomone Labs is pleased to offer the KCNQ Channel Antibody Explorer Kit (#AK-221). This Explorer Kit includes antibodies targeted against KV7 channels and subunits along with their respective peptide control antigen. An ideal tool for screening purposes.
- Compounds
- Scientific Background
- Related Products
| Product Name | Cat # | Size |
|---|---|---|
Anti-KV7.1 (KCNQ1) |
APC-022 | 1 x 50 µl |
Anti-KV7.1 (KCNQ1) (extracellular) |
APC-168 | 1 x 50 µl |
Anti-KV7.3 (KCNQ3) |
APC-051 | 1 x 50 µl |
Anti-KV7.4 |
APC-164 | 1 x 50 µl |
Anti-KV7.5 |
APC-155 | 1 x 50 µl |
Anti-KCNE3 (MiRP2) |
APC-118 | 1 x 50 µl |
Anti-KCNE4 (MiRP3) |
APC-129 | 1 x 50 µl |
KCNQ Channel Antibody Explorer KitScientific Background
The KCNQ family of voltage-gated K+ channels includes 5 known members: KCNQ1 to KCNQ5. Structurally, the KCNQ family belongs to the six transmembrane domain category of K+ channels. KCNQ family members can form either homomultimeric or heteromultimeric channels with different functional consequences. For example KCNQ2 and KCNQ3 heteromultimers give rise to a much larger channel current than when either protein is expressed alone, probably due to enhanced plasma membrane expression of the combined channel. Indeed, KCNQ2/KCNQ3 heteromultimers are believed to be the molecular correlates of the so-called M current. This current is a K+ neuronal current that is strongly inhibited by the activation of the M1 subtype of the muscarinic acetylcholine receptor.
KV7.5 is also expressed in visceral smooth muscle4 and skeletal muscle.
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