- 询价
- R&D
- ZK-0002433
- 美国/中国
- 2025年11月20日
- 科研使用
- Goat，Rabbit，Mouse
- 人，大鼠，小鼠，兔
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- 详细信息
- 技术资料
- 靶点：
来电咨询
- 克隆性：
多克隆
- 标记物：
见 说 明 书
- 宿主：
Goat，Rabbit，Mouse
- 适应物种：
人，大鼠，小鼠，兔
- 形态：
液态/粉状
- 应用范围：
科研使用
- 浓度：
1mg/1ml
- 保存条件：
-20℃保存
- Estrogen Receptor (CO1531) Monoclonal Antibody, Purified (SIGNET)详细信息：
-
Description Purified Monoclonal Antibody against Estrogen Receptor (CO1531)
(Formerly Signet Catalog Nos: 670-01, 670-26 L2 Predilute)Intended Use **Research Use Only (RUO)**
This product is sold for laboratory research use only, not for human or in-vivo use.Clone CO1531 Form Purified Antibody (in 0.01M PBS + 0.1% NaN3 + 1% BSA) Host Estrogen Receptor (CO1531) Monoclonal Antibody, Purified (SIGNET)Mouse Species Reactivity Human IsoType IgG2a Specificity Monoclonal Estrogen Receptor (ER) antibody clone CO1531 is directed against the beta form of estrogen receptor. Like other steroid hormone receptors, Estrogen Receptors are intracellular proteins. Estrogen Receptors play an important role in regulating mammary gland growth and differentiation.
Breast tumors that are ER positive may also show a more favorable response to anti-estrogen therapies.
Concentrated Format:
SIG-3670-1000 [1 mL]
Prediluted Formats:
SIG-3670-26 [6 mL] is ready-to-use with biotin-based detection systems such as USA Ultra Streptavidin Detection (SIG-32250) or with ACUITYAdvanced Biotin Free Polymer Detection System.Uses Estrogen Receptor (CO1531) Monoclonal Antibody, Purified (SIGNET)This antibody is effective in immunohistochemistry (IHC). Suggested Working Dilution The optimal working dilution should be determined for each specific assay condition. - IHC: ≥1:40 (concentrated format) with for Biotin based detection systems such as USA Ultra Streptavidin Detection (SIG-32250).
Tissue Sections: Formalin-fixed, paraffin-embedded tissues
Pretreatment: For optimal staining, the sections should be pretreated with an antigen unmasking solution such as Retrieve-All 1 (SIG-31910).
Incubation: 60 minutes at room temperature
Notes Positive tissue (human): Breast cancer tissue Storage Store between 2-8°C. References Schultz J, et al. Differential modulation of DNA conformation by estrogen receptors α and β. J Biol Chem 277(10): 8702-8707, 2002. Warranty/Conditions Covance products may not be resold or modified for resale without prior written approval. - IHC: ≥1:40 (concentrated format) with for Biotin based detection systems such as USA Ultra Streptavidin Detection (SIG-32250).
- Estrogen Receptor (CO1531) Monoclonal Antibody, Purified (SIGNET)
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Estrogen Receptor (CO1531) Monoclonal Antibody, Purified (SIGNET)
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