BioSIM 抗人 GDF8/Myostatin 抗体 (阿

BioSIM 抗人 GDF8/Myostatin 抗体 (阿匹特古单抗)，生物类似药，科研用途

产品概述

BioSIM anti-Human GDF8/Myostatin Antibody (Apitegromab Biosimilar) 是一种高特异性研究级抗体，针对人类生长分化因子8(GDF8)/肌肉生长抑制素(Myostatin)设计。作为阿匹特古单抗的生物类似药，该抗体专为科研用途开发，适用于多种实验技术平台，尤其在脊髓性肌萎缩(SMA)研究领域具有重要应用价值。

技术参数

• 产品名称：BioSIM 抗人 GDF8/Myostatin 抗体 (阿匹特古单抗)，生物类似药，科研用途
• 英文名称：BioSIM anti-Human GDF8/Myostatin Antibody (Apitegromab Biosimilar), Research Grade
• CAS号：2278276-46-1
• 产品类型：二抗
• 供应商：InvivoCrown
• 产品货号：SIM0487-5mg
• 产品规格：5mg
• 来源宿主：Human
• 反应性：Human

产品特点

• 作为阿匹特古单抗的生物类似抗体，具有高度特异性
• 在无动物成分的设施中生产，确保研究的一致性和可重复性
• 采用体外无蛋白细胞培养技术，避免潜在动物源污染
• 经过多步骤纯化工艺，包括Protein A或G色谱，确保高纯度
• 适用于多种实验技术，包括ELISA、FACS和功能性分析
• 支持体内研究应用，为临床前研究提供可靠工具

研究领域与应用

本抗体主要应用于脊髓性肌萎缩(SMA)的研究领域，同时也可用于其他与肌肉生长和发育相关的疾病研究，如肌营养不良症、肌肉萎缩症等。

应用类型

• ELISA：适用于酶联免疫吸附测定，可用于定量分析GDF8/Myostatin表达水平
• FACS：流式细胞术应用，可用于检测细胞表面或细胞内的GDF8/Myostatin表达
• Functional assay：功能性分析，可用于评估GDF8/Myostatin的生物活性
• Research in vivo：体内研究应用，可用于动物模型研究

保存与处理

• 保存建议：避免反复冻融，以确保抗体活性
• 短期保存（1-2周）：4°C
• 中期保存（最长12个月）：-20°C
• 长期保存：-80°C
• 使用前请轻轻混匀，避免产生气泡
• 使用无菌技术操作，防止微生物污染

订购信息

• 产品货号：SIM0487-5mg
• 包装规格：5mg
• 供应商：InvivoCrown

免疫原信息

BioSIM 抗人 GDF8/Myostatin 抗体的免疫原信息请参考该产品的说明书。详细的使用方法和注意事项请查阅随产品附带的技术文档。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human GDF8/Myostatin Antibody (Apitegromab Biosimilar), Research Grade

Product Overview

BioSIM anti-Human GDF8/Myostatin Antibody (Apitegromab Biosimilar) is a highly specific research-grade antibody designed against Human Growth Differentiation Factor 8 (GDF8)/Myostatin. As a biosimilar of Apitegromab, this antibody is specifically developed for research purposes, suitable for various experimental technology platforms, and holds significant application value in the research field of Spinal Muscular Atrophy (SMA).

Technical Parameters

• Product Name: BioSIM anti-Human GDF8/Myostatin Antibody (Apitegromab Biosimilar), Research Grade
• English Name: BioSIM anti-Human GDF8/Myostatin Antibody (Apitegromab Biosimilar), Research Grade
• CAS Number: 2278276-46-1
• Product Type: Secondary Antibody
• Supplier: InvivoCrown
• Catalog Number: SIM0487-5mg
• Specifications: 5mg
• Host Origin: Human
• Reactivity: Human

Product Features

• As a biosimilar antibody of Apitegromab, it exhibits high specificity
• Produced in animal-free facilities to ensure research consistency and reproducibility
• Utilizes protein-free in vitro cell culture technology to avoid potential animal-derived contaminants
• Processed through multi-step purification, including Protein A or G chromatography, to ensure high purity
• Compatible with various experimental techniques including ELISA, FACS, and functional assays
• Supports in vivo research applications, providing a reliable tool for preclinical studies

Research Fields and Applications

This antibody is primarily applied in the research field of Spinal Muscular Atrophy (SMA), and can also be used for studying other diseases related to muscle growth and development, such as muscular dystrophy, muscle atrophy, etc.

Application Types

• ELISA: Suitable for enzyme-linked immunosorbent assay, can be used for quantitative analysis of GDF8/Myostatin expression levels
• FACS: Flow cytometry application, can be used to detect cell surface or intracellular GDF8/Myostatin expression
• Functional assay: Functional analysis, can be used to evaluate the biological activity of GDF8/Myostatin
• Research in vivo: In vivo research application, can be used for animal model studies

Storage and Handling

• Storage Recommendation: Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term storage (1-2 weeks): 4°C
• Medium-term storage (up to 12 months): -20°C
• Long-term storage: -80°C
• Gently mix before use to avoid bubble formation
• Use aseptic techniques during handling to prevent microbial contamination

Ordering Information

• Catalog Number: SIM0487-5mg
• Packing Size: 5mg
• Supplier: InvivoCrown

Immunogen Information

Please refer to the product manual for immunogen information of BioSIM anti-Human GDF8/Myostatin Antibody. For detailed usage instructions and precautions, please consult the technical documentation accompanying the product.

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yaokein Company.