- 询价
- InvivoCrown
- 英国
- SIM0457-5mg
- 2025年11月10日
- ELISA, FACS, Functional assay, Research in vivo
- Humanized
- Human
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- 详细信息
- 文献和实验
- 技术资料
- 免疫原：
该BioSIM 抗人 PD-1/CD279 抗体 (诺法利单抗)，生物类似药，科研用途 [ CAS: 2377845-98-0]的免疫原请参考该产品的说明书
- 保存条件：
为确保适当储存，请避免反复冻融。短期需求（1-2周）请在4°C下保存；最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 克隆性：
单克隆
- 适应物种：
Human
- 保质期：
为确保适当储存，请避免反复冻融。短期需求（1-2周）请在4°C下保存；最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 级别：
科研级别
- 库存：
999
- 供应商：
亚科因(Abbkine)
- 宿主：
Humanized
- 应用范围：
ELISA, FACS, Functional assay, Research in vivo
- 抗体英文名：
PD-1/CD279
- 抗体名：
PD-1/CD279
- 规格：
5mg
BioSIM 抗人 PD-1/CD279 抗体 (诺法利单抗) - 科研级生物类似药
产品基本信息
产品名称：BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar), Research Grade
中文名称：BioSIM 抗人 PD-1/CD279 抗体 (诺法利单抗)，生物类似药，科研用途
CAS号：2377845-98-0
产品类型：二抗
供应商：InvivoCrown
产品货号：SIM0457-5mg
产品规格：5mg
产品概述
BioSIM 抗人 PD-1/CD279 抗体是一种高特异性的人源化抗体，作为诺法利单抗的生物类似药，专为科研用途设计。该抗体针对程序性死亡受体-1(PD-1/CD279)进行靶向结合，适用于多种免疫相关研究，尤其在肝细胞癌(HCC)研究领域具有广泛应用价值。
产品特点
- 生产工艺：在无动物成分的设施中生产，确保产品纯净度
- 细胞培养：采用体外无蛋白细胞培养技术，减少交叉污染风险
- 纯化工艺：经过多步骤纯化过程，包括Protein A或G亲和色谱工艺，确保高纯度
- 来源宿主：人源化设计，降低免疫原性
- 反应特异性：特异性识别人源PD-1/CD279分子
应用领域
BioSIM 抗人 PD-1/CD279 抗体适用于多种科研应用：
- ELISA检测：用于定量分析PD-1/CD279表达水平
- FACS分析：用于流式细胞术检测细胞表面PD-1/CD279表达
- 功能检测：评估PD-1/CD279通路在免疫应答中的作用
- 体内研究：探索PD-1/CD279在疾病模型中的生物学功能
- 重点研究领域：肝细胞癌(HCC)发病机制及免疫治疗研究
技术参数
| 参数 | 值 |
| 免疫原性 | 请参考产品说明书 |
| 来源宿主 | Humanized |
| 反应性 | Human |
| 纯度 | 经多步纯化工艺处理 |
储存条件
为确保抗体活性和稳定性，请遵循以下储存建议：
- 短期储存(1-2周)：4°C
- 中期储存(最长12个月)：-20°C
- 长期储存：-80°C
- 注意事项：避免反复冻融，以免影响抗体活性
产品优势
作为诺法利单抗的生物类似药，BioSIM 抗人 PD-1/CD279 抗体具有以下优势：
- 严格的质量控制标准，确保批次间一致性
- 无动物成分生产环境，减少批次间差异
- 适用于多种免疫学研究方法，提供实验灵活性
- 专注于肝细胞癌研究领域的应用优化
使用建议
在使用BioSIM 抗人 PD-1/CD279 抗体前，请仔细阅读产品说明书。根据具体实验设计，优化抗体浓度和孵育条件。建议进行预实验以确定最佳工作浓度，确保实验结果的可靠性和可重复性。
注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。
BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar) - Research Grade
Product Basic Information
Product Name: BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar), Research Grade
Chinese Name: BioSIM Anti-Human PD-1/CD279 Antibody (Nofazinlimab), Biosimilar, for Research Use
CAS Number: 2377845-98-0
Product Type: Secondary Antibody
Supplier: InvivoCrown
Catalog Number: SIM0457-5mg
Product Specification: 5mg
Product Overview
BioSIM anti-Human PD-1/CD279 Antibody is a highly specific humanized antibody designed as a biosimilar of Nofazinlimab for research purposes. This antibody targets and binds to Programmed Death Receptor-1 (PD-1/CD279), making it suitable for various immunology-related studies, with particular value in hepatocellular carcinoma (HCC) research.
Product Features
- Production Process: Produced in animal component-free facilities to ensure product purity
- Cell Culture: Utilizes protein-free in vitro cell culture technology to reduce the risk of cross-contamination
- Purification Process: Undergoes multi-step purification, including Protein A or G affinity chromatography, to ensure high purity
- Source Host: Humanized design to reduce immunogenicity
- Reaction Specificity: Specifically recognizes human PD-1/CD279 molecules
Application Areas
BioSIM anti-Human PD-1/CD279 Antibody is suitable for various research applications:
- ELISA detection: For quantitative analysis of PD-1/CD279 expression levels
- FACS analysis: For flow cytometry detection of cell surface PD-1/CD279 expression
- Functional assays: To evaluate the role of PD-1/CD279 pathway in immune responses
- In vivo studies: To explore the biological functions of PD-1/CD279 in disease models
- Key Research Area: Hepatocellular carcinoma (HCC) pathogenesis and immunotherapy research
Technical Parameters
| Parameter | Value |
| Immunogenicity | Please refer to the product manual |
| Source Host | Humanized |
| Reactivity | Human |
| Purity | Processed through multi-step purification |
Storage Conditions
To ensure antibody activity and stability, please follow the storage recommendations below:
- Short-term storage (1-2 weeks): 4°C
- Medium-term storage (up to 12 months): -20°C
- Long-term storage: -80°C
- Precautions: Avoid repeated freeze-thaw cycles to prevent affecting antibody activity
Product Advantages
As a biosimilar of Nofazinlimab, BioSIM anti-Human PD-1/CD279 Antibody offers the following advantages:
- Strict quality control standards to ensure batch-to-batch consistency
- Animal component-free production environment to reduce inter-batch variations
- Compatible with various immunology research methods, providing experimental flexibility
- Optimized for applications in hepatocellular carcinoma research
Usage Recommendations
Before using BioSIM anti-Human PD-1/CD279 Antibody, please carefully read the product manual. Optimize antibody concentration and incubation conditions according to specific experimental designs. It is recommended to perform preliminary experiments to determine the optimal working concentration to ensure reliable and reproducible experimental results.
Note: The information above may be subject to changes due to product optimization and upgrades. For specific information, please consult Yaokein Company.
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