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- 详细信息
- 技术资料
- 保存条件:
本品可在2-8°C保存12个月。请避免长期接触阳光,不要冻结。
- 保质期:
12个月
- 规格:
20Tests/100Tests/100Tests×2
| 规格: | 20Tests | 产品价格: | ¥1200.0 |
|---|---|---|---|
| 规格: | 100Tests | 产品价格: | ¥3120.0 |
| 规格: | 100Tests×2 | 产品价格: | ¥4680.0 |
| Alternate Names |
PD1, PDCD1, Protein PD-1, hPD-1
|
| Cellular Localization |
Membrane
|
| Clone No |
EH12.2H7
|
| Isotype |
Mouse IgG1, κ
|
| Leadtime |
咨询
|
| Background |
Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
|
| Abbre |
CD279
|
| Swissprot |
Q15116
|
| Host |
Mouse
|
| Reactivity |
Human
|
| Clonality |
Monoclonal
|
| Isotype Control |
Elab Fluor®700 Mouse IgG1, κ Isotype Control[MOPC-21]
|
| Applications |
FCM
|
| Form |
Liquid
|
| Conjugation |
Elab Fluor®700
|
| Conjugation Information |
Elab Fluor® 700 is designed to be excited by the Red laser (627-640 nm) and detected using an optical filter centered near 719 nm (e.g., a 725/40 nm bandpass filter).
|
| Storage Buffer |
Phosphate buffered solution, pH 7.2, containing 0.09% sodium azide and 1% BSA.
|
| Storage |
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
|
| Expiration Date |
12个月
|
| Shipping |
冰袋
|
| Gene ID |
5133
|
Staining of the MOLT-4 cells with Elab Fluor®700 Anti-Human CD279/PD-1 Antibody[EH12.2H7](filled gray histogram) or Elab Fluor®700 Mouse IgG1, κ Isotype Control(empty black histogram).Total viable cells were used for analysis.
| E-CK-A105 | 10×ACK Lysis Buffer | 500mL , 200mL , 100mL |
| E-CK-A107 | Cell Staining Buffer | 500mL , 200mL , 100mL |
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Elab Fluor®700 Anti-Human CD279/PD-1 Antibody[EH12.2H7]
¥1200 - 4680


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