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- 文献和实验
- 技术资料
- 免疫原:
该BioSIM 抗人 PD-1/CD279 抗体 (诺法利单抗),生物类似药,科研用途 [ CAS: 2377845-98-0]的免疫原请参考该产品的说明书
- 保存条件:
为确保适当储存,请避免反复冻融。短期需求(1-2周)请在4°C下保存;最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 克隆性:
单克隆
- 适应物种:
Human
- 保质期:
为确保适当储存,请避免反复冻融。短期需求(1-2周)请在4°C下保存;最长12个月的储存请在-20°C下保存。长期储存请在-80°C下保存。
- 级别:
科研级别
- 库存:
999
- 供应商:
亚科因(Abbkine)
- 宿主:
Humanized
- 应用范围:
ELISA, FACS, Functional assay, Research in vivo
- 抗体英文名:
PD-1/CD279
- 抗体名:
PD-1/CD279
- 规格:
1mg
BioSIM 抗人 PD-1/CD279 抗体 (诺法利单抗),生物类似药,科研用途
产品基本信息
| 产品名称: | BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar), Research Grade |
| 中文名称: | BioSIM 抗人 PD-1/CD279 抗体 (诺法利单抗),生物类似药,科研用途 |
| 供应商: | InvivoCrown |
| 产品货号: | SIM0457-1mg |
| 产品规格: | 1mg |
| CAS号: | 2377845-98-0 |
| 产品类型: | 二抗 |
产品概述
BioSIM 抗人 PD-1/CD279 抗体是一种高品质的生物类似药,针对程序性死亡受体-1(PD-1/CD279)的人源化抗体,专为科研用途设计。PD-1/CD279是免疫检查点蛋白,在调节T细胞功能中发挥关键作用,是肿瘤免疫治疗的重要靶点。该抗体是在严格的无动物成分设施中生产,采用先进的体外无蛋白细胞培养技术,并通过多步骤纯化过程,包括Protein A或G色谱工艺,确保产品的高纯度和一致性。
产品特点
- 高特异性: 精确靶向人源PD-1/CD279蛋白,阻断其与配体的相互作用
- 无动物成分: 在无动物成分的设施中生产,降低潜在交叉污染风险
- 先进生产工艺: 采用体外无蛋白细胞培养技术,确保产品纯净性
- 严格质控: 经过多步骤纯化过程,包括Protein A或G色谱工艺
- 人源化设计: 来源宿主为人源化,提高与人类靶点的亲和力
技术参数
| 反应性 | Human |
| 来源宿主 | Humanized |
| 研究领域 | 肝细胞癌(HCC) |
| 免疫原 | 参考产品说明书 |
应用领域
BioSIM 抗人 PD-1/CD279 抗体适用于多种科研应用:
- ELISA: 用于检测样本中PD-1/CD279蛋白的表达水平,支持免疫相关研究
- FACS: 用于流式细胞术分析,检测细胞表面PD-1/CD279的表达,评估免疫细胞状态
- Functional assay: 用于评估抗体对PD-1/CD279功能的影响,研究其在免疫调节中的作用
- Research in vivo: 用于体内研究,探索PD-1/CD279在疾病模型中的作用机制,特别是在肝细胞癌模型中的应用
保存与处理
为确保产品活性和稳定性,请遵循以下保存建议:
- 避免反复冻融,以保持抗体活性
- 短期保存(1-2周): 4°C
- 中期保存(最长12个月): -20°C
- 长期保存: -80°C
订购信息
| 产品货号: | SIM0457-1mg |
| 规格: | 1mg |
| 供应商: | InvivoCrown |
注意:以上信息可能随着产品优化升级等因素产生变动,具体信息请咨询亚科因公司。

BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar), Research Grade
Product Basic Information
| Product Name: | BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar), Research Grade |
| Chinese Name: | BioSIM anti-Human PD-1/CD279 Antibody (Nofazinlimab Biosimilar), Research Grade |
| Supplier: | InvivoCrown |
| Catalog Number: | SIM0457-1mg |
| Product Specification: | 1mg |
| CAS Number: | 2377845-98-0 |
| Product Type: | Secondary Antibody |
Product Overview
BioSIM anti-Human PD-1/CD279 Antibody is a high-quality biosimilar, a humanized antibody targeting Programmed Death Receptor-1 (PD-1/CD279), designed specifically for research purposes. PD-1/CD279 is an immune checkpoint protein that plays a crucial role in regulating T cell function and is an important target for cancer immunotherapy. This antibody is produced in strict animal component-free facilities using advanced animal-free cell culture technology and undergoes a multi-step purification process, including Protein A or G chromatography, to ensure high purity and consistency of the product.
Product Features
- High Specificity: Precisely targets human PD-1/CD279 protein, blocking its interaction with ligands
- Animal Component-Free: Produced in animal component-free facilities, reducing the risk of potential cross-contamination
- Advanced Production Process: Utilizes animal-free cell culture technology to ensure product purity
- Strict Quality Control: Undergoes multi-step purification, including Protein A or G chromatography
- Humanized Design: Derived from humanized host, enhancing affinity to human targets
Technical Parameters
| Reactivity | Human |
| Host Source | Humanized |
| Research Area | Hepatocellular Carcinoma (HCC) |
| Immunogen | Refer to product manual |
Application Areas
BioSIM anti-Human PD-1/CD279 Antibody is suitable for various research applications:
- ELISA: Used to detect the expression level of PD-1/CD279 protein in samples, supporting immune-related research
- FACS: Used for flow cytometry analysis to detect cell surface expression of PD-1/CD279 and assess immune cell status
- Functional assay: Used to evaluate the effect of the antibody on PD-1/CD279 function and study its role in immune regulation
- Research in vivo: Used for in vivo studies to explore the mechanism of action of PD-1/CD279 in disease models, especially in hepatocellular carcinoma models
Storage and Handling
To ensure product activity and stability, please follow the storage recommendations below:
- Avoid repeated freeze-thaw cycles to maintain antibody activity
- Short-term storage (1-2 weeks): 4°C
- Medium-term storage (up to 12 months): -20°C
- Long-term storage: -80°C
Ordering Information
| Catalog Number: | SIM0457-1mg |
| Specification: | 1mg |
| Supplier: | InvivoCrown |
Note: The above information may change due to factors such as product optimization and upgrades. Please consult Yakeyin Company for specific information.
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