BioSIM 抗人 IL-1b 抗体 (吉伏组单抗)，生物类

BioSIM 抗人 IL-1b 抗体 (吉伏组单抗)，生物类似药，科研用途

产品概述

BioSIM anti-Human IL-1b Antibody (Gevokizumab Biosimilar), Research Grade 是一种高品质的生物类似抗体，专为科研用途设计。该产品与治疗性抗体Gevokizumab共享相同的可变区结构，确保了其在研究应用中的特异性和可靠性。作为一款科研级产品，它为研究人员提供了研究IL-1β信号通路及其在多种疾病中作用的宝贵工具。

产品详情

• 产品名称：BioSIM 抗人 IL-1b 抗体 (吉伏组单抗)，生物类似药，科研用途
• CAS号：1129435-60-4
• 产品类型：二抗
• 供应商：InvivoCrown
• 产品货号：SIM0363-1mg
• 产品规格：1mg
• 来源宿主：人源化 (Humanized)
• 反应性：人源 (Human)

产品特性与应用

吉伏组单抗是一种完全人源化单克隆抗体，能够特异性地与人IL-1β结合。IL-1β是一种由单核细胞衍生的关键促炎细胞因子，在多种炎症性疾病和癌症的发生发展中扮演重要角色。

作用机制

该抗体靶向IL-1β的一个独特表位，能够有效降低IL-1受体结合率，从而中和IL-1β的生物活性。这一特性使其成为研究IL-1β信号通路的理想工具。

研究领域

BioSIM 抗人 IL-1b 抗体适用于多种疾病机制的研究，包括但不限于：

• 结直肠癌 (CRC)
• 肾细胞癌
• 食道癌
• 胃癌
• 1型糖尿病
• 类风湿性关节炎
• 心血管疾病
• 炎症性疾病
• 癌症免疫疗法

应用类型

该抗体适用于多种实验平台，包括：

• ELISA (酶联免疫吸附测定)
• FACS (流式细胞术)
• 功能性实验 (Functional assay)
• 体内研究 (Research in vivo)

储存与稳定性

为确保产品的活性和稳定性，请遵循以下储存条件：

• 避免反复冻融，以保持抗体活性
• 短期储存(1-2周)： 4°C
• 中期储存(最长12个月)： -20°C
• 长期储存： -80°C

注意事项

关于该抗体的免疫原性信息，请参考产品说明书。本产品仅限科研使用，不适用于诊断或治疗目的。

订购信息

产品货号：SIM0363-1mg
规格：1mg
供应商：InvivoCrown

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Anti-Human IL-1b Antibody (Gevokizumab Biosimilar), Research Use

Product Overview

BioSIM anti-Human IL-1b Antibody (Gevokizumab Biosimilar), Research Grade is a high-quality biosimilar antibody designed specifically for research purposes. This product shares the same variable region structure as the therapeutic antibody Gevokizumab, ensuring its specificity and reliability in research applications. As a research-grade product, it provides researchers with a valuable tool for studying the IL-1β signaling pathway and its role in various diseases.

Product Details

• Product Name: BioSIM Anti-Human IL-1b Antibody (Gevokizumab Biosimilar), Research Use
• CAS Number: 1129435-60-4
• Product Type: Secondary Antibody
• Supplier: InvivoCrown
• Catalog Number: SIM0363-1mg
• Specification: 1mg
• Source Host: Humanized
• Reactivity: Human

Product Characteristics and Applications

Gevokizumab is a fully humanized monoclonal antibody that specifically binds to human IL-1β. IL-1β is a key pro-inflammatory cytokine derived from monocytes, playing an important role in the pathogenesis of various inflammatory diseases and cancers.

Mechanism of Action

This antibody targets a unique epitope of IL-1β, effectively reducing IL-1 receptor binding rates, thereby neutralizing the biological activity of IL-1β. This characteristic makes it an ideal tool for studying the IL-1β signaling pathway.

Research Areas

BioSIM Anti-Human IL-1b Antibody is suitable for studying the mechanisms of various diseases, including but not limited to:

• Colorectal Cancer (CRC)
• Renal Cell Carcinoma
• Esophageal Cancer
• Gastric Cancer
• Type 1 Diabetes
• Rheumatoid Arthritis
• Cardiovascular Diseases
• Inflammatory Diseases
• Cancer Immunotherapy

Application Types

This antibody is suitable for various experimental platforms, including:

• ELISA (Enzyme-Linked Immunosorbent Assay)
• FACS (Flow Cytometry)
• Functional Assays
• In Vivo Research

Storage and Stability

To maintain the product's activity and stability, please follow the storage conditions below:

• Avoid repeated freeze-thaw cycles to maintain antibody activity
• Short-term storage (1-2 weeks): 4°C
• Medium-term storage (up to 12 months): -20°C
• Long-term storage: -80°C

Precautions

For immunogenicity information about this antibody, please refer to the product manual. This product is for research use only and is not intended for diagnostic or therapeutic purposes.

Ordering Information

Catalog Number: SIM0363-1mg
Specification: 1mg
Supplier: InvivoCrown

Note: The information above may change due to product optimization and upgrades. Please contact Yakeyin Company for specific information.