BioSIM 抗人 Siglec-2/CD22 抗体 (贝妥

BioSIM 抗人 Siglec-2/CD22 抗体 (贝妥莫单抗) 生物类似药（科研用途）

英文名称：BioSIM anti-Human Siglec-2/CD22 Antibody (Bectumomab Biosimilar), Research Grade

产品核心概览

• 产品货号：SIM0091-5mg
• 产品规格：5mg
• 产品类型：二抗
• CAS号：158318-63-9
• 供应商：InvivoCrown
• 产品等级：科研级（仅用于实验室研究，不涉及临床应用）

生产工艺特性

该重组生物类似抗体遵循标准化生产流程，关键工艺特点如下：

• 在无动物成分的设施中生产，减少外源性污染物引入风险
• 采用体外无蛋白细胞培养技术，避免血清等动物源成分干扰实验结果
• 经多步骤纯化工艺（含Protein A/G色谱法），保障抗体纯度与生物活性一致性

技术参数详情

基础属性

• 来源宿主：Mouse（小鼠）
• 反应性：Human（人）
• 免疫原：具体信息请参考产品配套说明书

应用场景与研究方向

适用实验类型

• ELISA：可用于人CD22抗原的体外定量检测
• FACS（荧光激活细胞分选）：分析细胞表面Siglec-2/CD22的表达水平
• Functional assay（功能实验）：验证CD22相关的细胞功能调控机制
• Research in vivo（体内研究）：支持动物模型中的靶点功能探索（需结合实验设计）

聚焦研究领域

非霍奇金淋巴瘤（NHL）：CD22作为B细胞表面关键分子，在多种B细胞来源的非霍奇金淋巴瘤中高表达，本产品可助力该领域的靶点验证与机制研究。

储存与稳定性建议

为维持抗体活性，需严格遵循以下储存条件：

• 短期使用（1-2周）：4°C避光保存（避免反复开盖）
• 中期储存（≤12个月）：-20°C避光保存，禁止反复冻融
• 长期储存（>12个月）：-80°C避光保存，建议分装为小体积（如100μL/管）减少冻融次数

供应商说明

品牌：InvivoCrown

合规性：符合科研级抗体生产的质量控制标准

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM anti-Human Siglec-2/CD22 Antibody (Bectumomab Biosimilar), Research Grade

Product Name: BioSIM anti-Human Siglec-2/CD22 Antibody (Bectumomab Biosimilar), Research Grade

Product Core Overview

• Catalog Number: SIM0091-5mg
• Size: 5mg
• Product Type: Secondary Antibody
• CAS Number: 158318-63-9
• Supplier: InvivoCrown
• Product Grade: Research Grade (For laboratory research use only, not for clinical applications)

Manufacturing Process Characteristics

This recombinant biosimilar antibody follows standardized production processes, with key manufacturing characteristics as follows:

• Produced in animal component-free facilities to reduce the risk of introducing exogenous contaminants
• Utilizes in vitro protein-free cell culture technology to avoid interference from animal-derived components such as serum in experimental results
• Subjected to multi-step purification processes (including Protein A/G chromatography) to ensure antibody purity and consistency of biological activity

Technical Parameter Details

Basic Properties

• Host Source: Mouse
• Reactivity: Human
• Immunogen: For specific information, please refer to the product instruction manual

Application Scenarios and Research Directions

Applicable Experiment Types

• ELISA: Can be used for in vitro quantitative detection of human CD22 antigen
• FACS (Fluorescence-Activated Cell Sorting): Analysis of cell surface Siglec-2/CD22 expression levels
• Functional assay: Verification of CD22-related cellular function regulatory mechanisms
• Research in vivo: Supports target function exploration in animal models (requires appropriate experimental design)

Focused Research Areas

Non-Hodgkin's Lymphoma (NHL): As a key molecule on the surface of B cells, CD22 is highly expressed in various B cell-derived non-Hodgkin's lymphomas. This product can facilitate target validation and mechanism studies in this field.

Storage and Stability Recommendations

To maintain antibody activity, the following storage conditions must be strictly followed:

• Short-term use (1-2 weeks): Store at 4°C protected from light (avoid repeated opening of the cap)
• Medium-term storage (≤12 months): Store at -20°C protected from light, avoid repeated freeze-thaw cycles
• Long-term storage (>12 months): Store at -80°C protected from light, aliquoting into small volumes (e.g., 100μL/tube) is recommended to reduce freeze-thaw cycles

Supplier Information

Brand: InvivoCrown

Compliance: Meets quality control standards for research-grade antibody production

Note: The above information may be subject to change due to product optimization and upgrades. For specific information, please contact InvivoCrown.