BioSIM 人 LFA-3 & IgG 融合蛋白 (来伐西

BioSIM 人 LFA-3 & IgG 融合蛋白 (来伐西普) 生物类似药（科研用途）

产品基本信息

• 英文名称：BioSIM Human LFA-3 & IgG fusion protein (Alefacept Biosimilar), Research Grade
• 中文名称：BioSIM 人 LFA-3 & IgG 融合蛋白 (来伐西普)，生物类似药，科研用途
• CAS号：222535-22-0
• 产品类型：重组蛋白
• 供应商：InvivoCrown
• 产品货号：SIM0759-1mg
• 产品规格：1mg

生产工艺与背景

本重组生物类似药采用严格的科研级生产体系，保障产物纯度与实验一致性：

• 全程在无动物源设施中生产，规避外源性动物蛋白污染风险；
• 仅依赖体外无蛋白细胞培养技术，减少非目标蛋白干扰；
• 经多步纯化工艺精制，核心包含蛋白A/G亲和色谱步骤，提升目标蛋白回收率与纯度。

产品核心特性

• 表达系统：哺乳动物细胞（重组蛋白表达常用体系，保障蛋白正确折叠与活性）
• 缓冲液体系：PBS（pH 7.4），不含稳定剂或防腐剂，适配多种下游实验场景

应用领域

本产品适用于以下科研方向的实验研究：

• 再生障碍性贫血
• 银屑病关节炎
• 慢性移植物抗宿主病

储存与运输建议

为维持产品活性与稳定性，需严格遵循以下操作规范：

• 短期使用（1-2周）：4℃避光保存（避免频繁开盖）
• 中短期储存（12个月内）：-20℃低温冰箱保存
• 长期储存：-80℃超低温冰箱保存（可延长活性保持周期）
• 关键禁忌：严禁反复冻融循环，以免破坏蛋白空间结构影响实验结果

运输建议：运输过程采用低温冷链（干冰或冰袋+保温箱），到货后请立即转移至对应温度条件储存。

注意：以上信息可能随着产品优化升级等因素产生变动，具体信息请咨询亚科因公司。

BioSIM Human LFA-3 & IgG Fusion Protein (Alefacept Biosimilar), for Research Use

Product Basic Information

• English Name: BioSIM Human LFA-3 & IgG Fusion Protein (Alefacept Biosimilar), Research Grade
• Chinese Name: BioSIM Human LFA-3 & IgG Fusion Protein (Alefacept), Biosimilar, for Research Use
• CAS Number: 222535-22-0
• Product Type: Recombinant Protein
• Supplier: InvivoCrown
• Catalog Number: SIM0759-1mg
• Presentation: 1mg

Manufacturing Process and Background

This recombinant biosimilar is produced under a strict research-grade manufacturing system to ensure product purity and experimental consistency:

• Produced entirely in animal-free facilities to avoid the risk of exogenous animal protein contamination;
• Utilizes only protein-free cell culture technology in vitro to reduce interference from non-target proteins;
• Purified through a multi-step purification process, primarily including protein A/G affinity chromatography steps to enhance target protein recovery and purity.

Core Product Characteristics

• Expression System: Mammalian cells (common system for recombinant protein expression, ensuring proper protein folding and activity)
• Buffer System: PBS (pH 7.4), without stabilizers or preservatives, suitable for various downstream experimental applications

Application Areas

This product is suitable for experimental research in the following scientific fields:

• Aplastic Anemia
• Psoriatic Arthritis
• Chronic Graft-versus-Host Disease (cGVHD)

Storage and Transportation Recommendations

To maintain product activity and stability, strictly follow the following operational specifications:

• Short-term use (1-2 weeks): Store at 4°C protected from light (avoid frequent opening)
• Medium-term storage (within 12 months): Store in -20°C freezer
• Long-term storage: Store in -80°C ultra-low temperature freezer (can extend the activity maintenance period)
• Critical禁忌: Strictly avoid repeated freeze-thaw cycles to prevent damage to the protein's spatial structure which may affect experimental results

Shipping Recommendation: Use cold chain transportation during shipping (dry ice or ice packs + insulated box). Upon receipt, immediately transfer to the corresponding storage temperature conditions.

Note: The above information may change due to factors such as product optimization and upgrades. For specific information, please consult Yacoin company.