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FAF1 Rabbit pAb(bs-1348R)-50ul

/100ul/200ul
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  • ¥1180 - 2800
  • Bioss已认证
  • bs-1348R
  • 2025年10月25日
  • 产品信息以Bioss网站为准
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      50ul/100ul/200ul

    规格:50ul产品价格:¥1180.0
    规格:100ul产品价格:¥1980.0
    规格:200ul产品价格:¥2800.0
    产品编号bs-1348R
    英文名称FAF1 Rabbit pAb
    中文名称Fas相关1因子抗体
    英文别名Fas associated factor 1; CGI; FAF1 protein; Fas(TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; CGI 03; FAF1; FAF1_HUMAN; Fas associated protein factor 1; FAS-associated factor 1; UBX domain protein 3A; UBX domain-containing protein 12; UBX domain-containing protein 3A; UBXD12; UBXN3A; TNFRSF6 associated factor 1.
    产品应用IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500

    Not yet tested in other applications.
    Optimal working dilutions must be determined by the end user.

    交叉反应Rat (Human, Mouse, Chicken, Dog, Cow, Rabbit)
    抗体来源Rabbit
    免疫原KLH conjugated synthetic peptide derived from human FAF1
    亚型IgG
    性状Liquid
    纯化方法affinity purified by Protein A
    克隆类型Polyclonal
    理论分子量74 kDa
    浓度1mg/ml
    储存液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
    研究领域

    Cell Biology > Apoptosis > Intracellular > Associated Proteins

    亚基Specifically interacts with the cytoplasmic domain of FAS. Interacts with NLRP12 DAPIN/PYRIN domain via its UBA domain.
    亚细胞定位Nucleus.
    组织特异性Most abundant in testis, slightly less abundant in skeletal muscle and heart, followed by prostate, thymus, ovary, small intestine, and colon. Not detected in the peripheral blood leukocytes.
    相似性Contains 1 UBA domain.
    Contains 1 UBX domain.
    功能Potentiates but cannot initiate FAS-induced apoptosis.
    保存条件Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料FAF1 (Fas-associated protein factor 1) specifically interacts with the cytoplasmic domain of wild type, but not mutated, Fas in both yeast and mammalian cells. It is transiently expressed in T cells and potentiates Fas-induced apoptosis. FAF1 lacks a DDH (Death domain homologous region), in contrast to TRADD, FADD, and RIP, and cannot induce apoptosis independent of Fas activation. Fas associated factor 1; CGI ; FAF1 protein; Fas (TNFRSF6) associated factor 1; FAS associated factor 1; FLJ37524; hFAF1; HFAF1s; Protein FAF1; TNFRSF6 associated factor 1.

     

    应用推荐稀释比例
    {IHC-P}{1:100-500}
    {IHC-F}{1:100-500}
    {IF}{1:100-500}

     

    产品细节图片1
    Tissue/cell: Rat testis tissue; 4% P‌‌araformaldehyde-fixed and paraffin-embedded;
    Antigen retrieval: citrate buffer ( 0.01M, pH 6.0 ), Boiling bathing for 15min; Block endogenous peroxidase by 3% Hydrogen peroxide for 30min; Blocking buffer (normal goat serum,C-0005) at 37℃ for 20 min;
    Incubation: Anti-FAF1 Polyclonal Antibody, Unconjugated(bs-1348R) 1:200, overnight at 4°C, followed by conjugation to the secondary antibody(SP-0023) and DAB(C-0010) staining
    产品细节图片2
    P‌‌araformaldehyde-fixed, paraffin embedded (rat colon); Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min; Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes; Blocking buffer (normal goat serum) at 37°C for 30min; Antibody incubation with (FAF1) Polyclonal Antibody, Unconjugated (bs-1348R) at 1:200 overnight at 4°C, followed by operating according to SP Kit(Rabbit) (sp-0023) instructionsand DAB staining.

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    图标文献和实验
    该产品被引用文献

    [IF={{ 2.583 }}] {He XY et al. C18H17NO6 and Its Combination with Scutellarin Suppress the Proliferation and Induce the Apoptosis of Human Glioma Cells via Upregulation of Fas-Associated Factor 1 Expression. BioMed Research International.2019.} {WB} {Human}

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    文献支持
    FAF1 Rabbit pAb(bs-1348R)-50ul/100ul/200ul
    ¥1180 - 2800