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- bs-17733R
- 2025年10月25日
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| 规格： | 50ul | 产品价格： | ￥1180.0 |
|---|---|---|---|
| 规格： | 100ul | 产品价格： | ￥1980.0 |
| 规格： | 200ul | 产品价格： | ￥2800.0 |
| 产品编号 | bs-17733R |
| 英文名称 | MOXD1 Rabbit pAb |
| 中文名称 | 单加氧酶X抗体 |
| 英文别名 | DBH like monooxygenase protein 1; DBH-like monooxygenase protein 1; dJ248E1.1; DKFZp564G202; Monooxygenase X; monooxygenase, DBH like 1; MOX; Moxd1; MOXD1_HUMAN; PRO5780. |
| 产品应用 | WB=1:500-2000, IHC-P=1:100-500, IHC-F=1:100-500, IF=1:100-500 Not yet tested in other applications. |
| 交叉反应 | Human, Mouse (Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep) |
| 抗体来源 | Rabbit |
| 免疫原 | KLH conjugated synthetic peptide derived from human MOXD1 |
| 亚型 | IgG |
| 性状 | Liquid |
| 纯化方法 | affinity purified by Protein A |
| 克隆类型 | Polyclonal |
| 理论分子量 | 68 kDa |
| 浓度 | 1mg/ml |
| 储存液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 研究领域 | Tags & Cell Markers > Subcellular Markers > Organelles > ER |
| 亚细胞定位 | Endoplasmic reticulum membrane. |
| 组织特异性 | Highly expressed in lung, kidney, brain and spinal cord. |
| 翻译后修饰 | N-glycosylated. |
| 相似性 | Belongs to the copper type II ascorbate-dependent monooxygenase family. Contains 1 DOMON domain. |
| 保存条件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MOXD1 is a 613 amino acid single-pass type I membrane protein of the Endoplasmic reticulum that belongs to the copper type II ascorbate-dependent monooxygenase family. Existing as two alternatively spliced isoforms, MOXD1 is expressed in adult spinal cord, adrenal gland, brain, testis, uterus, lung and kidney, as well as fetal liver and brain. MOXD1 is upregulated during replicative senescence in primary fibroblast and umbilical vein endothelial cell cultures, and uses two copper ions per subunit as a cofactor. MOXD1 contains one DOMON domain, undergoes post-translational N-glycosylation and is encoded by a gene that maps to human chromosome 6. Chromosome 6 contains 170 million base pairs, comprises nearly 6% of the human genome and is associated with early onset intestinal cancer, Porphyria cutanea tarda, Parkinson's disease and Stickler syndrome. |
| 应用 | 推荐稀释比例 |
| {WB} | {1:500-2000} |
| {IHC-P} | {1:100-500} |
| {IHC-F} | {1:100-500} |
| {IF} | {1:100-500} |
Jurkat(Human) Cell Lysate at 30 ug
Primary: Anti-MOXD1 (bs-17733R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 68 kD
Observed band size: 68 kD
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文献和实验[IF={{ 8.786 }}] {Jia-hao Bao. et al. Identification of a novel cuproptosis-related gene signature and integrative analyses in patients with lower-grade gliomas.. FRONT IMMUNOL. 2022 Aug;13:933973-933973} {WB} {Human}
[IF={{ 7.162 }}] {Jia Minxue. et al. Early events marking lung fibroblast transition to profibrotic state in idiopathic pulmonary fibrosis. RESP RES. 2023 Dec;24(1):1-13} {IHC,IF} {Human}
= NAL), appears to form upon oxidative cyclization of the nonfluorescent 2:1 lysine-HNE Michael adduct-Schiff base cross-link (Scheme 1). Polyclonal antibody (PAb) to the NAL-HNE fluorophore was raised in rabbit and found to be highly specific
GE Healthcare Benzamidine Sepharose™ 6B is p-aminobenzamidine covalently attached to Sepharose 6B by the epoxy coupling method. p-Aminobenzamidine (PAB), is a synthetic inhibitor of trypsin-like serine protease. Trypsin and trypsin
Nucleic Acid Programmable Protein Arrays: Versatile Tools for Array‐Based Functional Protein Studies
.g., Sigma) 50 mg/ml bis‐sulfosuccinimdylsuberate (BS3 ;Pierce, cat. no. PI 21580) in dimethylsulfoxide (DMSO) 5 mg/ml
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