3-(p-tert-butylphenyl)-2-methy

三句话读懂一篇 CNS：复旦大学研究表明，种花、种草有助预防多种疾病；打呼噜可能增加老年痴呆的风险

，美国匹兹堡 Dorothy P. 与 Richard P. Simmons 医学中心 Jonathan K. Alder 研究组与美国圣克鲁兹基因组研究所 Carol W. Greider 研究组联合在 Science 杂志发表研究论文 TPP1 promoter mutations cooperate with TERT promoter mutations to lengthen telomeres in melanoma。 该研究检测了来自 ICGC 联盟中黑色素瘤中端粒相关基因的体

Synthesis of Building Blocks and Oligonucleotides with {G}O6‐Alkyl‐O6{G} Cross‐Links

Introduction Basic Protocol 1: Protection of the Diol with a tert‐Butyldiphenyl Silyl Group Basic Protocol 2: Synthesis of O6‐2′‐Deoxyguanosine‐Alkyl‐O6‐2′‐Deoxyguanosine‐3′‐O‐bis‐Phosphoramidites

Synthesis of Peptidomimetic Conjugates of Cyclic Nucleoside Phosphonates

phosphonates connected through a P?O?C linkage to a promoiety represent a class of prodrugs designed to overcome the low oral bioavailability of parent antiviral acyclic nucleoside phosphonates. In our prodrug approach, a nontoxic promoiety, such as an amino