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- 文献和实验
- 技术资料
- 免疫原:
External domain of human TSH receptor.
- 亚型:
IgG2a
- 形态:
Purified IgG - liquid
- 克隆性:
Monoclonal Antibody
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
4C1
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
C, F, P
- 浓度:
IgG concentration 1.0 mg/ml
- 抗体名:
Thyroid Stimulating Hormone Receptor antibody | 4C1
- 规格:
20 µg/0.2 mg
| 规格: | 20 µg | 产品价格: | 询价 |
|---|---|---|---|
| 规格: | 0.2 mg | 产品价格: | 询价 |
Mouse anti Human thyroid stimulating hormone receptor, clone 4C1 recognizes the human thyroid stimulating hormone receptor (hTSHR), otherwise known as the thyrotropin receptor. Mouse anti Human thyroid stimulating hormone receptor, clone 4C1 binds to an extracellular domain of hTSHR.
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | × | ||
| Flow Cytometry | ✓ | 1/100 | 1/1000 |
| Immunohistology - Frozen | ✓ | ||
| Immunohistology - Paraffin | ✓ | 1/1000 | 1/2000 |
| Immunoprecipitation | ✓ | ||
| Western Blotting | ✓ | 1/1000 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
- Flow Cytometry
- Use 10μl of the suggested working dilution to label 106 cells in 100μl
- Histology Positive Control Tissue
- Human thyroid gland
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文献和实验该产品被引用文献
References for Thyroid Stimulating Hormone Receptor antibody
- (0) Human Protein Atlas: CAB000473
Human Protein Atlas: CAB000473 - Shepherd PS,et al. (1999) Identification of an important thyrotrophin binding site on the human thyrotrophin receptor using monoclonal antibodies.
Mol Cell Endocrinol.149:197-206. - Suh, J.M. et al. (2003) Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland.
J Biol Chem. 278 (24): 21960-71. - Kleinau, G. et al. (2011) From Molecular Details of the Interplay between Transmembrane Helices of the Thyrotropin Receptor to General Aspects of Signal Transduction in Family A G-protein-coupled Receptors (GPCRs).
J Biol Chem. 286: 25859-71. - Oba, J. et al. (2017) Trends in hepatocyte growth factor, insulin-like growth factor 1, thyroid-stimulating hormone, and leptin expression levels in uveal melanoma patient serum and tumor tissues: correlation to disease progression.
Melanoma Res. 27 (2): 126-33.
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Mouse anti Human Thyroid Stimulating Hormone Receptor,clone 4C1
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