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- 详细信息
- 技术资料
- 免疫原:
A peptide within the N-terminal region of human PRMT2
- 亚型:
PRMT2
- 形态:
Purified IgG - liquid
- 克隆性:
Polyclonal Antibody
- 标记物:
Purified
- 适应物种:
Human
- 保质期:
自发货之日起 12 个月
- 目录编号:
Polyclonal IgG
- 供应商:
伯乐生命医学产品(上海)有限公司
- 应用范围:
IF, WB
- 抗体名:
PRMT2 antibody
- 规格:
0.1 ml
Rabbit anti Human PRMT2 antibody recognizes protein arginine N-methyltransferase 2.
PRMT2 methylates arginyl residues in proteins such as STAT3, FBL, histone H4 and functions as a coactivator of androgen receptor (AR)-mediated and estrogen receptor (ER)-mediated transactivation (Qi et al. 2002, Meyer et al. 2007). PRMT2 may inhibit NF-kappa-B transcription and promote apoptosis involved in growth regulation (Ganesh et al. 2006). In humans, the C-terminal domain of pol II (CTD) comprises 52 repeats of the consensus heptapeptide Tyr1/Ser2/Pro3/Thr4/Ser5/Pro6/Ser7 that is phosphorylated by several kinases during transcription (Zaborowska et al. 2016).
PRMT2 methylates arginyl residues in proteins such as STAT3, FBL, histone H4 and functions as a coactivator of androgen receptor (AR)-mediated and estrogen receptor (ER)-mediated transactivation (Qi et al. 2002, Meyer et al. 2007). PRMT2 may inhibit NF-kappa-B transcription and promote apoptosis involved in growth regulation (Ganesh et al. 2006). In humans, the C-terminal domain of pol II (CTD) comprises 52 repeats of the consensus heptapeptide Tyr1/Ser2/Pro3/Thr4/Ser5/Pro6/Ser7 that is phosphorylated by several kinases during transcription (Zaborowska et al. 2016).
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended. Should this product contain a precipitate we recommend microcentrifugation before use.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| Immunofluorescence | ✓ | 1/2000 | |
| Western Blotting | ✓ | 1/500 | 1/2500 |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
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Rabbit anti Human PRMT2
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