- 询价
- BIO-RAD
- MCA6289B
- 2025年10月17日
- E
- Human
企业认证
相关产品推荐更多 >
万千商家帮你免费找货
0 人在求购买到急需产品
- 详细信息
- 技术资料
- 免疫原：
CHO derived recombinant full length human vWF (Met1-Lys2813)
- 亚型：
IgG2b
- 形态：
Purified IgG conjugated to Biotin - liquid
- 克隆性：
Monoclonal Antibody
- 标记物：
Biotin
- 适应物种：
Human
- 保质期：
自发货之日起 12 个月
- 目录编号：
E01-1C8
- 供应商：
伯乐生命医学产品（上海）有限公司
- 应用范围：
E
- 浓度：
IgG concentration 0.1 mg/ml
- 抗体名：
vWF antibody | E01-1C8
- 规格：
0.1 mg
Mouse anti Human vWF antibody, clone E01-1C8, recognizes von Willebrand factor (vWF) a multifunctional glycoprotein that plays essential roles in primary and secondary homeostasis, mediates platelet adhesion and is a carrier of coagulation factor VIII (Yasar et al. 2018).
vWF is present in blood plasma, the subendothelial matrix, platelet granules (α granules) and endothelial cells (Kawecki et al. 2017). In endothelial cells, the vWF is stored in mature Weibel-Palade bodies before it is secreted into the plasma (Yasar et al. 2018). vWF plasma levels are influenced by genetic, pathological, hormonal and environmental interactions (Swystun & Lillicrap 2018). Upon vascular injury, vWF mediates the anchoring of platelets to the subendothelium leading to the formation of a platelet plug and the arrest of bleeding. Due to its acute release by the activated epithelium, vWF has been considered a marker of inflammation in various pathologies. However there is evidence that vWF is able to play a direct role in inflammation by recruiting leukokcytes to sites of inflammation (Kawecki et al. 2017).
The biotinylated Mouse anti Human vWF antibody, clone E01-1C8 (MCA6289B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human vWF antibody, clone C01-1F2 (MCA6288GA) as the capture antibody.
vWF is present in blood plasma, the subendothelial matrix, platelet granules (α granules) and endothelial cells (Kawecki et al. 2017). In endothelial cells, the vWF is stored in mature Weibel-Palade bodies before it is secreted into the plasma (Yasar et al. 2018). vWF plasma levels are influenced by genetic, pathological, hormonal and environmental interactions (Swystun & Lillicrap 2018). Upon vascular injury, vWF mediates the anchoring of platelets to the subendothelium leading to the formation of a platelet plug and the arrest of bleeding. Due to its acute release by the activated epithelium, vWF has been considered a marker of inflammation in various pathologies. However there is evidence that vWF is able to play a direct role in inflammation by recruiting leukokcytes to sites of inflammation (Kawecki et al. 2017).
The biotinylated Mouse anti Human vWF antibody, clone E01-1C8 (MCA6289B) can be used as a detection antibody in a sandwich ELISA with the purified Mouse anti Human vWF antibody, clone C01-1F2 (MCA6288GA) as the capture antibody.
储存信息
This product is shipped at ambient temperature. It is recommended to aliquot and store at -20°C on receipt. When thawed, aliquot the sample as needed. Keep aliquots at 2-8°C for short term use (up to 4 weeks) and store the remaining aliquots at -20°C.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
Avoid repeated freezing and thawing as this may denature the antibody. Storage in frost-free freezers is not recommended.
应用
This product has been reported to work in the following applications. This information is derived from testing within our laboratories, peer-reviewed publications or personal communications from the originators. Please refer to references indicated for further information. For general protocol recommendations, please visit the antibody protocols page.
| Application Name | Verified | Min Dilution | Max Dilution |
|---|---|---|---|
| ELISA | ✓ | 1.0 ug/ml |
Where this product has not been tested for use in a particular technique this does not necessarily exclude its use in such procedures. Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own system using appropriate negative/positive controls.
风险提示：丁香通仅作为第三方平台，为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全，合理判断，谨慎选购商品，商家和用户对交易行为负责。对于医疗器械类产品，请先查证核实企业经营资质和医疗器械产品注册证情况。
技术资料暂无技术资料 索取技术资料
Mouse anti Human vWF:Biotin，clone E01-1C8
询价
