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- bs-4478P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-4478P |
| 英文名称 | TMPRSS3 Antibody Blocking Peptide |
| 中文名称 | 跨膜丝氨酸蛋白酶3封闭多肽 |
| 英文别名 | Deafness autosomal recessive 10; DFNB10; DFNB8; ECHOS1; Gene similar to transmembrane serine protease; MGC130589; Serine protease TADG-12; si:dz69g10.3; TADG12; TMPRSS 3; TMPRSS3; TMPS3_HUMAN; Transmembrane protease serine 3; Tumor associated differentially expressed gene 12 protein; Tumor-associated differentially-expressed gene 12 protein; UNQ323/PRO382. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > TMPRSS Neuroscience > Neurology process > Neurodegenerative disease |
| 亚细胞定位 | Endoplasmic reticulum membrane. |
| 组织特异性 | Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas. |
| 翻译后修饰 | Undergoes autoproteolytic activation. |
| 相似性 | Belongs to the peptidase S1 family. Contains 1 LDL-receptor class A domain. Contains 1 peptidase S1 domain. Contains 1 SRCR domain. |
| 功能 | Probable serine protease that play a role in hearing. Acts as a permissive factor for cochlear hair cells survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity). Activates ENaC (in vitro). |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a serine protease domain, a transmembrane domain, an LDL receptor-like domain, and a scavenger receptor cysteine-rich domain. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified by its association with both congenital and childhood onset autosomal recessive deafness. This gene is expressed in fetal cochlea and many other tissues, and is thought to be involved in the development and maintenance of the inner ear or the contents of the perilymph and endolymph. This gene was also identified as a tumor-associated gene that is overexpressed in ovarian tumors. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2012] |
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TMPRSS3 Antibody Blocking Peptide(bs-4478P)-500ug
￥880
