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- Bioss
- bs-11348P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-11348P |
| 英文名称 | Hippocalcin Antibody Blocking Peptide |
| 中文名称 | 神经细胞特异性钙结合蛋白封闭多肽 |
| 英文别名 | BDR 2; BDR2; Calcium binding protein BDR 2; Calcium binding protein BDR2; Calcium-binding protein BDR-2; Hpca; HPCA_HUMAN; Neuron specific calcium binding protein hippocalcin; Neuron specific calcium-binding protein hippocalcin; Neuron-specific calcium-binding protein hippocalcin; P23K. |
| 纯化方法 | HPLC |
| 组织特异性 | Brain specific. |
| 翻译后修饰 | Myristoylation facilitates interaction with membranes. |
| 相似性 | Belongs to the recoverin family. Contains 4 EF-hand domains. |
| 功能 | May be involved in the calcium-dependent regulation of rhodopsin phosphorylation. Binds two calcium ions. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Hippocalcin is a neuron-specific calcium-binding protein found primarily in the plasma membrane of brain and retinal tissue, with increased expression observed in hippocampal pyramidal cells. Through its calcium-dependent signal regulation, hippocalcin can both inhibit rhodopsin kinase and increase phospholipase D2 expression. In order to regulate kinase and phospholipase activity, hippocalcin must bind to the plasma membrane where it can then bind two calcium ions for use in signal regulation. The hippocalcin protein is highly conserved in mouse, rat and human tissue and has a suggested role in neural plasticity and associative memory by contributing to the survival of neurons during aging. The loss of hippocalcin expression is thought to contribute to age-related impairment of post-synaptic functions related to neuronal degradation. |
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Hippocalcin Antibody Blocking Peptide(bs-11348P)-500ug
￥880
