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- Bioss
- bs-9259P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9259P |
| 英文名称 | RNF169 Antibody Blocking Peptide |
| 中文名称 | 环指蛋白169封闭多肽 |
| 英文别名 | KIAA1991; RING finger protein 169; RN169_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Other Antibodies > Other Antibodies |
| 亚细胞定位 | Nucleus, nucleoplasm. Note=Localizes to sites of double-strand breaks (DSBs) following DNA damage. Recruited to DSBs via recognition of RNF168-dependent ubiquitin products. |
| 相似性 | Belongs to the RNF169 family. Contains 1 RING-type zinc finger. |
| 功能 | Probable E3 ubiquitin-protein ligase that acts as a negative regulator of double-strand breaks (DSBs) repair following DNA damage. Recruited to DSB repair sites by recognizing and binding ubiquitin catalyzed by RNF168 and competes with TP53BP1 and BRCA1 for association with RNF168-modified chromatin, thereby acting as a negative regulator of DSBs repair. E3 ubiquitin-protein ligase activity is not required for regulation of DSBs repair. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | RNF169 contains 1 RING type zinc finger. The exact functions of RNF169 remain unknown. |
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RNF169 Antibody Blocking Peptide(bs-9259P)-500ug
￥880
