PCDHB12 Antibody Blocking Peptide(bs-13732P)-500ug

PCDHB12 Antibody Blocking Pept

ide(bs-13732P)-500ug
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  • ¥880
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  • bs-13732P
  • 2025年10月16日
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      500ug

    产品编号bs-13732P
    英文名称PCDHB12 Antibody Blocking Peptide
    中文名称钙粘蛋白β12封闭多肽
    英文别名PCDBC_HUMAN; PCDH beta12; PCDH-beta-12; PCDHB 12; PCDHB12; Protocadherin beta 12; Protocadherin beta-12.
    纯化方法HPLC
    亚细胞定位Cell membrane; Single-pass type I membrane protein.
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster. Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs. As a result, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein. Localized to the cell membrane, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains. PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain.

     

     

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