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- Bioss
- bs-9252P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-9252P |
| 英文名称 | RNF130 Antibody Blocking Peptide |
| 中文名称 | 环指蛋白130封闭多肽 |
| 英文别名 | GOLIATH; 2510042A13Rik; G1 related zinc finger protein; G1rp; G1RZFP; GP antibody MGC117241; MGC138647; MGC99542; R goliath; RING finger protein 130; GOLI_HUMAN. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein (Potential). Cytoplasm. |
| 组织特异性 | Ubiquitously expressed. Highly expressed in leukocytes. Not expressed in erythroblasts. |
| 翻译后修饰 | In vivo measurements suggest this protein is glycosylated (PubMed:19159218). In contrast, in vitro experiments failed to detect glycosylation (PubMed:16549277). |
| 相似性 | Contains 1 PA (protease associated) domain. Contains 1 RING-type zinc finger. |
| 功能 | May have a role during the programmed cell death of hematopoietic cells. Acts as an E3 ubiquitin-protein ligase. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The RING-type zinc finger motif is present in a number of viral and eukaryotic proteins and is made of a conserved cysteine-rich domain that is able to bind two zinc atoms. Proteins that contain this conserved domain are generally involved in the ubiquitination pathway of protein degradation. RNF130 (ring finger protein 130), also known as GP, G1RZFP (G1-related zinc finger protein) or GOLIATH, is a 419 amino acid single-pass type I membrane protein that shares similarity with a Drosophila zinc-finger protein found in mesoderm known as g1. RNF130 contains one PA (protease associated) domain and a single RING-type zinc finger. Implicated in the regulation of growth factor withdrawal-induced apoptosis of myeloid precursor cells, RNF130 is encoded by a gene located on human chromosome 5q35.3 and mouse chromosome 11 B1.3. |
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RNF130 Antibody Blocking Peptide(bs-9252P)-500ug
￥880
