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- Bioss
- bs-1104P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-1104P |
| 英文名称 | TBX2 Antibody Blocking Peptide |
| 中文名称 | 新型抑癌基因封闭多肽 |
| 英文别名 | T-bet; T-box2; T-box Protein 2; T-box transcription factor TBX2; T-box protein 2; FLJ10169; HGNC: 11597; T box 2; T box transcription factor TBX2; TBX2; TBX2_HUMAN. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Oncoproteins > Transcription factors Epigenetics and Nuclear Signaling > Transcription > Cancer susceptibility > Proto-oncogenes Epigenetics and Nuclear Signaling > Transcription > Transcription Factors |
| 亚基 | Interacts with PML (isoform-PML-2, isoform PML-3 and isoform PML-4). |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Expressed primarily in adult in kidney, lung, and placenta. Weak expression in heart and ovary. |
| 相似性 | Contains 1 T-box DNA-binding domain. |
| 功能 | Involved in the transcriptional regulation of genes required for mesoderm differentiation. Probably plays a role in limb pattern formation. Acts as a negative regulator of PML function in cellular senescence. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene. |
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TBX2 Antibody Blocking Peptide(bs-1104P)-500ug
￥880
