- ￥880
- Bioss
- bs-13523P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13523P |
| 英文名称 | GPR20 Antibody Blocking Peptide |
| 中文名称 | G蛋白偶联受体20封闭多肽 |
| 英文别名 | G protein coupled receptor 20; G-protein coupled receptor 20; Gpr20; GPR20_HUMAN; GPCR GPR20. |
| 纯化方法 | HPLC |
| 研究领域 | Neuroscience > Neurotransmission > Receptors / Channels > GPCR > More GPCR Signal Transduction > Signaling Pathway > G Protein Signaling > GPCR |
| 亚细胞定位 | Cell membrane. |
| 组织特异性 | Ubiquitous with highest levels in intestinal tissues. In the brain detected in thalamus, putamen, and caudate, but not in frontal cortex, pons and hypothalamus. |
| 相似性 | Belongs to the G-protein coupled receptor 1 family. |
| 功能 | Orphan receptor with constitutive G(i) signaling activity that activate cyclic AMP. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR20 is a 358 amino acid membrane protein that constitutively activates G(i) proteins without ligand stimulation. Also, GPR20 may be involved in the control of intracellular cAMP levels and mitogenic signaling. Interestingly, GPR20 is expressed in liver and certain regions of the brain, including putamen, caudate and thalamus, but is not expressed in hypothalamus, pons and frontal cortex. |
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GPR20 Antibody Blocking Peptide(bs-13523P)-500ug
￥880
