- ￥880
- Bioss
- bs-7886P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-7886P |
| 英文名称 | AFF4 Antibody Blocking Peptide |
| 中文名称 | 淋巴细胞相关AF4样蛋白封闭多肽 |
| 英文别名 | Alf4; Laf4; MGC107469; AF4/FMR2 family member 4; AF5Q31; ALL1 fused gene from chromosome 5q31; HSPC092; Lymphoid nuclear protein related to AF4 like; Major CDK9 elongation factor associated protein; MCEF; RP23-226J16.7; AFF4_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Cell Cycle > Cyclins > Other Cyclins Epigenetics and Nuclear Signaling > Cell cycle > Cyclins > Other Cyclins Epigenetics and Nuclear Signaling > Transcription > Other factors Epigenetics and Nuclear Signaling > Transcription > Transcription Factors |
| 亚基 | Component of the cyclin-dependent kinase pair(CDK9/cyclin-T1) complex, also called positive transcriptionelongation factor b (P-TEFb). |
| 亚细胞定位 | Nucleus. |
| 组织特异性 | Ubiquitously expressed. Strongly expressed inheart, placenta, skeletal muscle, pancreas and to a lower extent inbrain. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. [DISEASE] Note=A chromosomal aberration involving AFF4 is found inacute lymphoblastic leukemia (ALL). Insertion ins(5;11)(q31;q13q23)that forms a MLL-AFF4 fusion protein. |
| 相似性 | Belongs to the AF4 family. |
| 功能 | May play a role in transcriptional regulation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | May play a role in transcriptional regulation. Component of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor b (P-TEFb). |
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AFF4 Antibody Blocking Peptide(bs-7886P)-500ug
￥880
