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500ug
| 产品编号 | bs-17473P |
| 英文名称 | SHQ1 Antibody Blocking Peptide |
| 中文名称 | SHQ1蛋白封闭多肽 |
| 英文别名 | FLJ10539; Protein SHQ1 homolog; shq1; SHQ1 homolog (S. cerevisiae); SHQ1 homolog; SHQ1, H/ACA ribonucleoprotein assembly factor; SHQ1_HUMAN; Shq1p. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > Translation > Regulation |
| 亚细胞定位 | Cytoplasm > cytosol. Nucleus > nucleoplasm. May at least partially shuttle between cytosol and nucleoplasm. In the nucleoplasm, exhibits a granular pattern, but is excluded from nucleoli and Cajal bodies. Absent from most H/ACA-box RNA transcription sites. |
| 相似性 | Belongs to the SHQ1 family. Contains 1 CS domain. |
| 功能 | Required for the quantitative accumulation of H/ACA ribonucleoproteins (RNPs), including telomerase, probably through the stabilization of DKC1, from the time of its synthesis until its association with NOP10, NHP2, and NAF1 at the nascent H/ACA RNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | SHQ1 assists in the assembly of H/ACA-box ribonucleoproteins that function in the processing of ribosomal RNAs, modification of spliceosomal small nuclear RNAs, and stabilization of telomerase (see MIM 602322) (Grozdanov et al., 2009 [PubMed 19383767]).[supplied by OMIM, Dec 2010] |
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SHQ1 Antibody Blocking Peptide(bs-17473P)-500ug
¥880







