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- 详细信息
- 技术资料
- 规格:
500ug
| 产品编号 | bs-9217P |
| 英文名称 | CST9 Antibody Blocking Peptide |
| 中文名称 | 胱抑素9/半胱氨酸蛋白酶抑制剂9封闭多肽 |
| 英文别名 | M12; CLM; Cresp; Cst9; CST9_HUMAN; Cystatin 9 (testatin); Cystatin like molecule; Cystatin-9; Cystatin-like molecule; Testatin. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted. May be targeted through the Golgi via the secretory pathway. |
| 组织特异性 | Expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. Not expressed in brain. Barely expressed in tumor cell lines except for breast adenocarcinoma MCF-7 cells and U251 cells. |
| 相似性 | Belongs to the cystatin family. |
| 功能 | May play a role in hematopoietic differentiation or inflammation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family, such as cathepsins, while some also inhibit legumain family enzymes. The CRES (cystatin-related epididymal spermatogenic) protein defines a new subgroup in the family 2 cystatins of the cystatin superfamily. CRES proteins lack two of the three consensus sites necessary for the cystatin inhibition of C1 cysteine proteases. Due to their expression patterns, it is likely that CRES proteins may perform unique and tissue-specific functions in the reproductive and neuroendocrine systems. As a member of the CRES subfamily, Cystatin 9, also designated CLM, is a 159 amino acid protein that is expressed in heart, placenta, lung, liver, skeletal muscle and pancreas. Cystatin 9 is thought to play a role in hematopoietic differentiation or inflammation. It has also been shown to be upregulated by LPS in some cancer cell lines, such as promyelocytic leukemia (HL-60) and myelomonocytic leukemia. |
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CST9 Antibody Blocking Peptide(bs-9217P)-500ug
¥880





