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- Bioss
- bs-10998P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-10998P |
| 英文名称 | phospho-IRS2 (Ser731) Antibody Blocking Peptide |
| 中文名称 | 磷酸化胰岛素受体底物2封闭多肽 |
| 英文别名 | IRS-2(phospho-Ser731); IRS-2(phospho S731); Insulin Receptor Substrate 2; IRS 2; IRS-2; IRS2; IRS2_HUMAN. |
| 纯化方法 | HPLC |
| 研究领域 | Cardiovascular > Atherosclerosis > Diabetes associated Metabolism > Pathways and Processes > Metabolic signaling pathways > Energy transfer pathways > Energy Metabolism Metabolism > Types of disease > Diabetes Metabolism > Types of disease > Heart disease Signal Transduction > Adapters > Cytoplasmic Signal Transduction > Growth Factors/Hormones > Insulin / Insulin-like Signal Transduction > Metabolism > Energy Metabolism |
| 亚基 | Interacts with PHIP. |
| 亚细胞定位 | Cytoplasm, cytosol. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Contains 1 IRS-type PTB domain.
Contains 1 PH domain. |
| 功能 | May mediate the control of various cellular processes by insulin. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The family of insulin receptor substrates (IRSs) has been reported to play important roles for signal transduction of various hormones. Four members of the IRS family have been described. Each IRS is believed to have different functions; however, the distinct physiological roles of each IRS are unclear. Summary: This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment. |
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phospho-IRS2 (Ser731) Antibody Blocking Peptide(bs-10998P)-500ug
￥1080
