Recombinant human TRABD2A (isoform2) protein(bs-49017P)-100ug/500ug/20ug

Recombinant human TRABD2A (iso

form2) protein(bs-49017P)-100ug/500ug/20ug
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  • ¥580 - 5680
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  • bs-49017P
  • 2025年10月16日
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      100ug/500ug/20ug

    规格:100ug产品价格:¥1880.0
    规格:500ug产品价格:¥5680.0
    规格:20ug产品价格:¥580.0
    产品编号bs-49017P
    英文名称Recombinant human TRABD2A (isoform2) protein
    中文名称重组人TRABD2A亚型2蛋白
    英文别名TraB Domain Containing 2A; TRAB Domain-Containing Protein 2A; C2orf89; TIKI1; Chromosome 2 Open Reading Frame 89; UPF0632 Protein C2orf89; Metalloprotease TIKI1; Recombinant human TRABD2A (isoform2) protein
    性状Lyophilized or Liqui
    纯化方法AC
    理论分子量56
    储存液10mM Tris-HCl (pH8.0) with 8M Urea and 10% Glycerol.
    亚细胞定位Membrane.
    相似性Belongs to the TIKI family.
    功能Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation.
    保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料[FUNCTION] Metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Following cleavage, Wnt proteins become oxidized and form large disulfide-bond oligomers, leading to their inactivation. Able to cleave WNT3A, WNT5, but not WNT11. Required for head formation. [COFACTOR] Divalent metal cations. Manganese or cobalt.

     

     

    Recombinant human TRABD2A (iso
    The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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