SUGT1 Antibody Blocking Peptide(bs-7831P)-500ug

SUGT1 Antibody Blocking Peptid

e(bs-7831P)-500ug
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  • bs-7831P
  • 2025年10月16日
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      500ug

    产品编号bs-7831P
    英文名称SUGT1 Antibody Blocking Peptide
    中文名称SUGT1蛋白封闭多肽
    英文别名Protein 40 6 3; Protein 40-6-3; Sgt1; SGT1 suppressor of G2 allele of SKP1; SGT1B protein; sugt1; SUGT1_HUMAN; Suppressor of G2 allele of SKP1 homolog; Suppressor of G2 allele of SKP1 S. cerevisiae homolog of.
    纯化方法HPLC
    研究领域

    Cell Biology > Cell Cycle > Cell Division > Other cell division antibodies

    Epigenetics and Nuclear Signaling > Cell cycle > Chromosome Structure > Chromatid Cohesion

    亚基Probably associates with SCF (SKP1-CUL1-F-box protein) complex through interaction with SKP1. Interacts with S100A6. Interacts with HSP90.
    亚细胞定位Cytoplasm {ECO:0000269|PubMed:21864708}. Nucleus {ECO:0000269|PubMed:21864708}. Note=Translocates to the nucleus upon heat shock, requiring S100A6.
    翻译后修饰Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex. {ECO:0000269|PubMed:21864708}.
    相似性Belongs to the SUGT1 family. Contains 1 CS domain. Contains 1 SGS domain. Contains 1 SGS domain.
    功能May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene is homologous to the yeast gene SGT1, which encodes a protein involved in kinetochore function and required for the G1/S and G2/M transitions. Complementation studies suggest that the human protein has similar functions. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].

     

     

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