OLFM1 Antibody Blocking Peptide(bs-2173P)-500ug

OLFM1 Antibody Blocking Peptid

e(bs-2173P)-500ug
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  • ¥880
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  • bs-2173P
  • 2025年10月16日
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      500ug

    产品编号bs-2173P
    英文名称OLFM1 Antibody Blocking Peptide
    中文名称嗅球蛋白1封闭多肽
    英文别名OLFM1; AMY; D2Sut1e; Neuronal olfactomedin-related ER localized protein; Noe1; Noel; Noel1; Noelin1; OlfA; Olfactomedin 1; Olfm1; Pancortin 1; Pancortin.
    性状Lyophilized
    纯化方法HPLC
    研究领域

    Neuroscience > Neurology process > Neurodegenerative disease

    Neuroscience > Neurology process > Neurogenesis

    Stem Cells > Neural Stem Cells > Intracellular

    亚细胞定位Endoplasmic reticulum lumen.
    相似性Contains 1 olfactomedin-like domain.
    功能Noelins belong to the olfactomedin family, which is comprised of extracellular proteins with proposed roles in neural and neural crest development.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    背景资料The Olfactomedin family comprises a diverse group of secreted glycoproteins, which includes OLFM1 (Noelin-1), OLFM2 (Noelin-2), OLFM3 (Noelin-3), OLFM4 (Noelin-4), tiarin, pancortin, gliomedin and mycocilin. These proteins are implicated in the development of the nervous system. Specifically, OLFM1 and OLFM2 expression is observed in the neural plate and neural crest, as well as in the cranial ganglia in mouse at E8-10, and later in brain tissue and in the zone of polarizing activity in the limb. Overexpression of OLFM1 causes an excess of neural crest emigrations and prolonged neural crest production. OLFM2 participates in the regulation of the development of the anterior nervous system. An Arg144Gln mutation in OLFM2 has been implicated as a possible cause for open-angle glaucoma (OAG).

     

     

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