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- bs-20208P
- 2025年10月16日
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500ug
| 产品编号 | bs-20208P |
| 英文名称 | CXCL2 Antibody Blocking Peptide |
| 中文名称 | 巨噬细胞炎症蛋白2（ GRO β）封闭多肽 |
| 英文别名 | C-X-C motif chemokine 2; Chemokine (C X C motif) ligand 2; Chemokine, CXC motif, ligand 2; CINC 2a; CINC2a; CINC3; CXC chemokine; CXCL 2; CXCL2; MIP2; MIP 2; MIP-2; Cytokine-induced neutrophil chemoattractant 3; GRO 2; GRO b; GRO protein, beta; Gro-beta; GRO2; GRO2 oncogene; GROb; GRObeta; GRO Beta; Growth regulated protein beta; GROX; Macrophage inflammatory protein 2 alpha; Macrophage inflammatory protein 2; Melanoma growth stimulatory activity beta; MGSA b; MGSA beta; MGSAbeta; MIP 2; MIP 2a; MIP2 alpha; MIP2; MIP2A; MIP2alpha; SCYB 2; Scyb; SCYB2; Small inducible cytokine subfamily B, member 2. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Chemokines > Alpha Chemokines (CXC) |
| 亚细胞定位 | Secreted. |
| 翻译后修饰 | The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells. |
| 相似性 | Belongs to the intercrine alpha (chemokine CxC) family. |
| 功能 | Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60% amino acid homology to human GRO alpha and GRO gamma. |
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CXCL2 Antibody Blocking Peptide(bs-20208P)-500ug
￥880
