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- Bioss
- bs-2624P
- 2025年10月16日
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500ug
| 产品编号 | bs-2624P |
| 英文名称 | IL22RA1 Antibody Blocking Peptide |
| 中文名称 | 白介素22受体封闭多肽 |
| 英文别名 | IL-22R; CRF2 9; IL22 Receptor Alpha; cytokine receptor classII member 9; cytokine receptor family 2 member 9; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL22R; IL22R1; IL22RA1; ILTIF R1 chain; Interleukin 22 Receptor alpha 1; Interleukin 22 Receptor; Interleukin-22 receptor subunit alpha-1; ZcytoR11; I22R1_HUMAN; IL-22 receptor subunit alpha-1; IL-22RA1; Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9. |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Cytokines > Interleukins Immunology > Innate Immunity > Macrophage / Inflamm. Signal Transduction > Adapters > Transmembrane |
| 亚基 | Heterodimer with IL10RB and with IL20RB. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed in kidney, liver and lung. |
| 相似性 | Belongs to the type II cytokine receptor family. Contains 2 fibronectin type-III domains. |
| 功能 | Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]. |
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IL22RA1 Antibody Blocking Peptide(bs-2624P)-500ug
￥880
