OIP5 Antibody Blocking Peptide(bs-8856P)-500ug

OIP5 Antibody Blocking Peptide

(bs-8856P)-500ug
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  • ¥880
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  • bs-8856P
  • 2025年10月16日
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      500ug

    产品编号bs-8856P
    英文名称OIP5 Antibody Blocking Peptide
    中文名称癌/睾丸抗原封闭多肽86封闭多肽
    英文别名5730547N13Rik; Cancer/testis antigen 86; CT 86; CT86; hMIS18beta; LAP2alpha interactor 25; LINT 25; LINT25; MIS18B; MIS18beta; MS18B_HUMAN; OIP 5; OIP-5; OIP5; Opa interacting protein 5; Opa-interacting protein 5; Protein Mis18-beta.
    纯化方法HPLC
    亚细胞定位Nucleus. Chromosome. Chromosome, centromere. Associated with centromeres in interphase cells, from late anaphase to the G1 phase. Not detected on centromeres during earlier phases of mitosis. Associated with chromatin.
    功能Required for recruitment of CENPA to centromeres and normal chromosome segregation during mitosis.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料OIP5 is a 229 amino acid nuclear protein that is required for chromosome segregation during mitosis. OIP5 exists as a homodimer but can also heterodimerize with FASP1 (FAPP1-associated protein 1). Essential for the recruitment of CENP-A (centromere autoantigen A) to centromeres, OIP5 localizes to centromeres of interphase cells during late anaphase and G1. The gene encoding OIP5 maps to human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

     

     

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