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- Bioss
- bs-2185P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-2185P |
| 英文名称 | TDRD9 Antibody Blocking Peptide |
| 中文名称 | 缺氧诱导蛋白HIG1封闭多肽 |
| 英文别名 | C14orf75; chromosome 14 open reading frame 75; HIG 1; HIG1; Hypoxia inducible HIG 1; MGC135025; Putative ATP dependent RNA helicase TDRD9; Putative ATP-dependent RNA helicase TDRD9; TDRD 9; Tdrd9; TDRD9_HUMAN ; Tudor domain containing 9; Tudor domain containing protein 9; Tudor domain-containing protein 9. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with piRNA-associated proteins PIWIL1 and PIWIL4 |
| 亚细胞定位 | Cytoplasm. Nucleus. Component of the nuage, also named P granule, a germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to piP-bodies, a subset of the nuage which contains secondary piRNAs. PIWIL2 is required for its localization to piP-bodies. |
| 相似性 | Belongs to the DEAD box helicase family. DEAH subfamily.
Contains 1 helicase ATP-binding domain. Contains 1 helicase C-terminal domain. Contains 1 Tudor domain. |
| 功能 | Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Probable ATP-binding RNA helicase which plays a central role during spermatogenesis by repressing transposable elements and prevent their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and govern the methylation and subsequent repression of transposons. Its association with PIWIL4 and the piP-bodies suggests a participation in the secondary piRNAs metabolic process. |
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TDRD9 Antibody Blocking Peptide(bs-2185P)-500ug
￥880
