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- Bioss
- bs-20183P
- 2025年10月16日
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- 规格：
500ug
| 产品编号 | bs-20183P |
| 英文名称 | CES2 Antibody Blocking Peptide |
| 中文名称 | 羧酸酯酶2封闭多肽 |
| 英文别名 | Carboxylesterase 2 (intestine, liver); Carboxylesterase 2; CE-2; CES2; CES2A1; Cocaine esterase; EC 3.1.1.1; EST2_HUMAN; hCE-2; ICE; Iintestinal carboxylesterase liver carboxylesterase 2; Intestinal carboxylesterase; liver carboxylesterase-2; Methylumbelliferyl acetate deacetylase 2; PCE 2; PCE-2. |
| 纯化方法 | HPLC |
| 研究领域 | Metabolism > Pathways and Processes > Metabolic signaling pathways > Drug metabolism Signal Transduction > Metabolism > Drug metabolism Signal Transduction > Metabolism > Lipid metabolism |
| 亚细胞定位 | Endoplasmic reticulum lumen. |
| 组织特异性 | Preferentially expressed in intestine with moderate expression in liver. Within the intestine, highest expression is found in small intestine with lower expression in colon and rectum. |
| 翻译后修饰 | Glycosylated. |
| 相似性 | Belongs to the type-B carboxylesterase/lipase family. |
| 功能 | Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Shows high catalytic efficiency for hydrolysis of Cocaine, 4-methyumbelliferyl acetate, heroin and 6-monoacetylMorphine. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics, such as Cocaine and heroin, and endogenous substrates with ester, thioester, or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism, and may play a role in the blood-brain barrier system. The protein encoded by this gene is the major intestinal enzyme and functions in intestine drug clearance. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2010] |
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CES2 Antibody Blocking Peptide(bs-20183P)-500ug
￥880
