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- bs-13982P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13982P |
| 英文名称 | COPZ1 Antibody Blocking Peptide |
| 中文名称 | 衣壳蛋白-ζ1封闭多肽 |
| 英文别名 | 5930435A22Rik; AA407760; CGI 120; Coatomer protein complex subunit zeta 1; Coatomer subunit zeta 1; Coatomer subunit zeta-1; COPZ; COPZ 1; COPZ1; COPZ1_HUMAN; D4Ertd360e; HSPC181; MGC118060; Zeta 1 coat protein; zeta 1 COP; zeta COP; Zeta-1 COP; Zeta-1-coat protein; Zeta1 COP. |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Protein Trafficking > ER Proteins Signal Transduction > Protein Trafficking > Golgi Proteins Signal Transduction > Protein Trafficking > Vesicle Transport > Coat Proteins Signal Transduction > Protein Trafficking > Vesicle Transport > Regulation |
| 亚细胞定位 | Cytoplasm. Golgi apparatus membrane. Cytoplasmic vesicle > COPI-coated vesicle membrane. The coatomer is cytoplasmic or polymerized on the cytoplasmic side of the Golgi, as well as on the vesicles/buds originating from it. |
| 翻译后修饰 | Phosphorylated upon DNA damage, probably by ATM or ATR. |
| 相似性 | Belongs to the adaptor complexes small subunit family. |
| 功能 | The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors. The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | This gene encodes a subunit of the cytoplasmic coatamer protein complex, which is involved in autophagy and intracellular protein trafficking. The coatomer protein complex is comprised of seven subunits and functions as the coat protein of coat protein complex (COP)I-vesicles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012] |
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COPZ1 Antibody Blocking Peptide(bs-13982P)-500ug
￥880
