- ￥880
- Bioss
- bs-8689P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-8689P |
| 英文名称 | MEPE Antibody Blocking Peptide |
| 中文名称 | 细胞外基质磷酸化封闭多肽 |
| 英文别名 | Matrix extracellular phosphoglycoprotein; MEPE; MEPE_HUMAN; OF45; Osteoblast/osteocyte factor 45. |
| 纯化方法 | HPLC |
| 亚细胞定位 | Secreted |
| 组织特异性 | Expressed by osteoblasts. Secreted from oncogenic hypophosphataemic tumors. |
| 翻译后修饰 | Phosphorylated (in vitro) by FAM20C in the extracellular medium at sites within the S-x-E/pS motif. |
| 功能 | Seems to play a role in mineralization. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | MEPE is a 525 amino acid extracellular matrix protein. Expressed in osteocytes and brain, MEPE is a regulator of bone metabolism that is thought to mediate mineralization and demineralization within the osteocyte microenvironment. MEPE contains an RGD cell-attachment motif and shares molecular similarities with several dentin-bone extracellular matrix RGD-containing phosphoglycoproteins, including OPN (osteopontin) and DSP (dentin sialophosphoprotein). Via its ability to control bone mineralization, MEPE is associated with various developmental events such as skeletogenesis, bone regeneration and odontogenesis. MEPE is secreted in hypophosphatemic osteomalacia tumors, suggesting a possible role in the pathophysiology of bone-related cancers. |
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MEPE Antibody Blocking Peptide(bs-8689P)-500ug
￥880
