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- bs-0567P
- 2025年10月16日
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500ug
| 产品编号 | bs-0567P |
| 英文名称 | ITGA5 Antibody Blocking Peptide |
| 中文名称 | 整合素α5封闭多肽 |
| 英文别名 | Integrin alpha-5 light chain; Alpha 5 beta 1; CD49 antigen-like family member E; CD49e; ECMRVI; Fibronectin Receptor alpha; Fibronectin receptor alpha subunit; Fibronectin receptor, alpha subunit; FNR; FNRA; gpIc/IIa; Integrin alpha 5 (fibronectin receptor alpha); Integrin alpha 5; Integrin alpha F; Integrin alpha-5; Integrin alpha-F; Integrin, alpha 5 (fibronectin receptor, alpha polypeptide); ITGA5; Very late Activation Antigen 5; Very Late Activation Protein 5 alpha; Very late activation protein 5, alpha subunit; VLA5; VLA5A; ITA5_HUMAN; Integrin α5; Integrin-α5. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Signal Transduction > Adapters > Transmembrane Signal Transduction > Cytoskeleton / ECM > Cell Adhesion > Integrins > Alpha Stem Cells > Endothelial Progenitors > Endothelial Markers Stem Cells > Hematopoietic Progenitors > Myeloid > Mast Cell Lineage |
| 亚基 | Heterodimer of an alpha and a beta subunit. The alpha subunit is composed of an heavy and a light chain linked by a disulfide bond. Alpha-5 associates with beta-1. Interacts with HPS5 and NISCH. Interacts with RAB21 and COMP. Interacts with HIV-1 Tat. |
| 亚细胞定位 | Membrane; Single-pass type I membrane protein. |
| 相似性 | Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats. |
| 功能 | CD49e is the integrin alpha 5 chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 5 undergoes post translational cleavage in the extracellular domain to yield disulfide linked light and heavy chains that join with beta 1 to form a fibronectin receptor that is known variously: in lymphocytes as very late (activation) antigen 5 (VLA5); in platelets as glycoprotein IcIIa; and in fibroblasts as extracellular matrix receptor 6 (ECMVI). In addition to adhesion, integrins are known to participate in cell surface mediated signalling. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 背景资料 | The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This gene encodes the integrin alpha 5 chain. Alpha chain 5 undergoes post-translational cleavage in the extracellular domain to yield disulfide-linked light and heavy chains that join with beta 1 to form a fibronectin receptor. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling. [provided by RefSeq, Jul 2008] |
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ITGA5 Antibody Blocking Peptide(bs-0567P)-500ug
￥880
