- ￥800
- Bioss
- bs-13130P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-13130P |
| 英文名称 | CFD Antibody Blocking Peptide |
| 中文名称 | 补体因子D封闭多肽 |
| 英文别名 | adipsin; Adipsin/complement factor D; adn; C3 convertase activator; CFAD_HUMAN; CFD; Complement factor D; complement factor D preproprotein; D component of complement; DF; FactorD; PFD; Properdin factor D. |
| 性状 | Lyophilized |
| 纯化方法 | HPLC |
| 研究领域 | Immunology > Innate Immunity > Complement > Alternative Pathway |
| 亚细胞定位 | Secreted. |
| 相似性 | Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. |
| 功能 | Factor D cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. Its function is homologous to that of C1s in the classical pathway. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Adipsin is the mouse homolog of the previously described human complement Factor D, a serine protease, which is now designated human Adipsin. Human Adipsin is highly expressed in and secreted by adipose tissue, and it has also been found in monocytes and macrophages. Rodent Adipsin has only been detected in high levels in adipose tissue. It has been shown that complement factor B, when complexed with activated complement component C3, is cleaved by Adipsin. While low expression of Adipsin has been confirmed in obese mice with hypothalamic defects, this inverse correlation between Adipsin expression and obesity has not been demonstrated in humans. |
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CFD Antibody Blocking Peptide(bs-13130P)-500ug
￥800
