TNXB Antibody Blocking Peptide(bs-20062P)-500ug

TNXB Antibody Blocking Peptide

(bs-20062P)-500ug
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  • bs-20062P
  • 2025年10月16日
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      500ug

    产品编号bs-20062P
    英文名称TNXB Antibody Blocking Peptide
    中文名称腱糖蛋白X封闭多肽
    英文别名Ehlers Danlos like syndrome; Hexabrachion like protein; Hexabrachion-like protein; HXBL; NXB2; Tenascin X precursor; Tenascin XB; Tenascin XB1; Tenascin XB2; Tenascin-X; TENX; TENX_HUMAN; TN X; TN-X; TNX; TNXB; TNXB1; TNXB2; TNXBS; XB; XBS.
    纯化方法HPLC
    研究领域

    Signal Transduction > Cytoskeleton / ECM > Extracellular Matrix > ECM Proteins > Tenascin

    亚细胞定位Secreted, extracellular space, extracellular matrix.
    组织特异性Highly expressed in fetal adrenal, in fetal testis, fetal smooth, striated and cardiac muscle. Isoform XB-short is only expressed in the adrenal gland.
    相似性Belongs to the tenascin family.
    Contains 19 EGF-like domains.
    Contains 1 fibrinogen C-terminal domain.
    Contains 32 fibronectin type-III domains.
    功能Appears to mediate interactions between cells and the extracellular matrix. Substrate-adhesion molecule that appears to inhibit cell migration. Accelerates collagen fibril formation. May play a role in supporting the growth of epithelial tumors.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料This gene encodes a member of the tenascin family of extracellular matrix glycoproteins. The tenascins have anti-adhesive effects, as opposed to fibronectin which is adhesive. This protein is thought to function in matrix maturation during wound healing, and its deficiency has been associated with the connective tissue disorder Ehlers-Danlos syndrome. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. It is one of four genes in this cluster which have been duplicated. The duplicated copy of this gene is incomplete and is a pseudogene which is transcribed but does not encode a protein. The structure of this gene is unusual in that it overlaps the CREBL1 and CYP21A2 genes at its 5' and 3' ends, respectively. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

     

     

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