- ￥880
- Bioss
- bs-15245P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-15245P |
| 英文名称 | C6orf25 Antibody Blocking Peptide |
| 中文名称 | 6号染色体开放阅读框25封闭多肽 |
| 英文别名 | Chromosome 6 open reading frame 25; G6b; G6B protein; Immunoglobulin receptor; MGC142279; MGC142281; NG31; Protein G6b;G6B_HUMAN. |
| 纯化方法 | HPLC |
| 亚基 | Interacts with PTPN6 and PTPN11. Binds to heparin. |
| 亚细胞定位 | Isoform E: Endoplasmic reticulum. Golgi apparatus. Isoform D: Endoplasmic reticulum. Golgi apparatus. Isoform B: Cell membrane; Single-pass type I membrane protein. Isoform A: Cell membrane; Single-pass type I membrane protein. |
| 组织特异性 | Expressed in a restricted set of hematopoietic cell lines including the erythroleukemia cell line K-562 and the T-cell leukemia cell lines MOLT-4 and Jurkat. Not detected in the monocyte-like cell line U-937, the B-cell-like cell line Raji, the fibroblast cell lines TK and HeLa, or the natural killer cell lines NKL, NK 62 and YT. Expressed in platelets. |
| 翻译后修饰 | All isoforms are N-glycosylated. Isoform E is O-glycosylated. |
| 功能 | Inhibits platelet aggregation and activation by agonists such as ADP and collagen-related peptide. Appears to operate in a calcium-independent manner. Isoform B is a putative inhibitory receptor. Isoform A may be its activating counterpart. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | C6orf25 is a member of the immunoglobulin (Ig) superfamily and is located in the major histocompatibility complex (MHC) class III region. It is a glycosylated, plasma membrane-bound cell surface receptor, but soluble isoforms encoded by some transcript variants have been found in the endoplasmic reticulum and Golgi before being secreted. Multiple transcript variants encoding different isoforms have been found for this gene. |
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C6orf25 Antibody Blocking Peptide(bs-15245P)-500ug
￥880
