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- 2025年10月16日
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| 产品编号 | bs-7955P |
| 英文名称 | TPTE Antibody Blocking Peptide |
| 中文名称 | 肿瘤/睾丸抗原44封闭多肽 |
| 英文别名 | Cancer/testis antigen 44; CT44; EC=3.1.3.48; HGNC:12023; PTEN2; Putative tyrosine protein phosphatase; Putative tyrosine-protein phosphatase TPTE; TPTE; TPTE_HUMAN; Transmembrane phosphatase with tensin homology; Tumor antigen BJ HCC 5; Tumor antigen BJ-HCC-5. |
| 纯化方法 | HPLC |
| 研究领域 | Cancer > Oncoproteins/suppressors > Tumor suppressors > PTEN pathway Cell Biology > Cell Cycle > Kinases/Phosphatases > Phosphatases Signal Transduction > Protein Phosphorylation > Tyrosine Phosphatases |
| 亚细胞定位 | Membrane; Multi-pass membrane protein. |
| 组织特异性 | Exclusively expressed in testis. |
| 相似性 | Contains 1 C2 tensin-type domain. Contains 1 phosphatase tensin-type domain. |
| 功能 | Could be involved in signal transduction. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | TPTE is a 551 amino acid multi-pass membrane protein belonging to the PTEN-related family that is exclusively expressed in the testis and localizes to the plasma membrane in humans. The gene encoding TPTE is present in multiple copies in the human genome, some of which may be pseudogenes. TPTE contains one C2 tensin-type domain and one phosphatase tensin-type domain but, in humans, it does not exhibit phosphatase activity. However, the mouse ortholog (PTEN2) is a functional 3-phosphoinositide phosphatase that localizes to the Golgi apparatus and plays a possible role in signal transduction. In humans, four isoforms, namely TPTEå, TPTE∫, TPTE© and TPTE∂, are produced by alternative splicing of this gene. |
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文献和实验or from the literature are missing. In this article, processing parameters for DNA, peptide, antibody, and carbohydrate microarrays are outlined. The applicability of the model experiments is demonstrated and described in detail on the example of short oligonucleotides.
Synthesis and Probing of Membrane-bound Peptide Arrays
the stringency of the blocking conditions and make sure that the primary binding partner and detection reagent (e.g., antibody) are of high purity and are used in the highest possible dilution. Stage
Mapping Protein‐Protein Interactions with Phage‐Displayed Combinatorial Peptide Libraries
. Fack, F., Deroo, S., Kreis, S., and Muller, C.P. 2000. Heteroduplex mobility assay (HMA) pre‐screening: An improved strategy for the rapid identification of inserts selected from phage‐displayed peptide
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