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500ug
| 产品编号 | bs-11183P |
| 英文名称 | TMPRSS5 Antibody Blocking Peptide |
| 中文名称 | 跨膜丝氨酸蛋白酶5封闭多肽 |
| 英文别名 | Spinesin; TMPRSS 5; TMPRSS-5; TMPRSS5; TMPS5_HUMAN; Transmembrane protease serine 5; Transmembrane protease, serine 5 (spinesin); Transmembrane protease, serine 5; MGC141886; MGC148044; OTTHUMP00000238209; OTTHUMP00000238210; OTTHUMP00000238211; OTTHUMP00000238212; OTTHUMP00000238213. |
| 纯化方法 | HPLC |
| 研究领域 | Cell Biology > Proteolysis / Ubiquitin > Proteolytic enzymes > Serine protease > TMPRSS |
| 亚细胞定位 | Cell membrane. |
| 翻译后修饰 | Brain-specific. Predominantly expressed in neurons, in their axons, and at the synapses of motoneurons in the spinal cord. |
| 相似性 | Belongs to the peptidase S1 family. Contains 1 peptidase S1 domain. Contains 1 SRCR domain. |
| 功能 | May play a role in hearing. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Extracellular proteases mediate the digestion of neiGHBoring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors. TMPRSS5 (transmembrane protease, serine 5), also known as spinesin, is a 457 amino acid single-pass type II membrane protein that is expressed specifically in brain and is thought to play a role in hearing. A member of the peptidase S1 family, TMPRSS5 contains one peptidase S1 domain and an SRCR domain, and is encoded by a gene that maps to human chromosome 11q23.2. Defects in the gene encoding TMPRSS5 are associated with deafness. |
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TMPRSS5 Antibody Blocking Peptide(bs-11183P)-500ug
¥880







