PCDHGA12 Antibody Blocking Peptide(bs-11152P)-500ug

PCDHGA12 Antibody Blocking Pep

tide(bs-11152P)-500ug
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  • ¥880
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  • bs-11152P
  • 2025年10月16日
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      500ug

    产品编号bs-11152P
    英文名称PCDHGA12 Antibody Blocking Peptide
    中文名称原钙粘蛋白γA12封闭多肽
    英文别名Cadherin 21; Cadherin21; Cadherin-21; CDH21; FIB3; Fibroblast cadherin FIB3; PCDH gamma A12; Protocadherin gamma subfamily A, 12; PCDGC_HUMAN.
    纯化方法HPLC
    亚细胞定位Cell membrane; Single-pass type I membrane protein.
    相似性Contains 6 cadherin domains.
    功能Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.
    保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
    注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    背景资料Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. The protocadherein gamma cluster consists of three subfamilies (A, B and C). As a member of the gamma subfamily A, PCDHGA12 (Protocadherin gamma A12), also known as Cadherin-21 and Fibroblast cadherin-3, is a 932 amino acid protein that is one of 22 proteins encoded by the protocadherin gamma cluster. Typical of gamma protocadherins, PCDHGA12 contains six cadherin motifs and is a type I transmembrane receptor expressed in the central nervous system. Ubiquitously expressed with lowest levels in spleen, PCDHGA12 is thought to be involved in cell signaling. There are three isoforms of PCDHGA12 that are produced as a result of alternative splicing events.

     

     

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