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- Bioss
- bs-12492P
- 2025年10月16日
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- 详细信息
- 技术资料
- 规格：
500ug
| 产品编号 | bs-12492P |
| 英文名称 | APOBEC1 Antibody Blocking Peptide |
| 中文名称 | 载脂蛋白B-mRNA编辑酶复合物1封闭多肽 |
| 英文别名 | ABEC1_HUMAN; APOBEC 1; APOBEC1; Apolipoprotein B mRNA editing enzyme; Apolipoprotein B mRNA editing enzyme catalytic polypeptide 1; Apolipoprotein B mRNA editing enzyme complex 1; Apolipoprotein B mRNA-editing enzyme 1; BEDP; C->U-editing enzyme APOBEC-1; CDAR1; EC 3.5.4.; HEPR. |
| 纯化方法 | HPLC |
| 研究领域 | Epigenetics and Nuclear Signaling > DNA / RNA > RNA Processing |
| 亚基 | Homodimer. Part of the apolipoprotein B mRNA editing complex with A1CF. Found in a complex with CELF2/CUGBP2 and A1CF. Interacts with HNRPAB and SYNCRIP. |
| 亚细胞定位 | Cytoplasm. |
| 组织特异性 | Expressed exclusively in the small intestine. |
| 相似性 | Belongs to the cytidine and deoxycytidylate deaminase family. |
| 功能 | Catalytic component of the apolipoprotein B mRNA editing enzyme complex which is responsible for the postranscriptional editing of a CAA codon for Gln to a UAA codon for stop in the APOB mRNA. Also involved in CGA (Arg) to UGA (Stop) editing in the NF1 mRNA. |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 背景资料 | Post-transcriptional editing of apolipoprotein B (apoB) mRNA is regulated by This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. [provided by RefSeq, Jul 2008]. |
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APOBEC1 Antibody Blocking Peptide(bs-12492P)-500ug
￥880
